Intralymphatic Histiocytosis and Cancer of the Colon

Echeverría-García, B.; Botella‐Estrada, Rafael; Requena, Celia; Guillén, C.

doi:10.1016/s1578-2190(10)70625-9

Cited by 8 publications

(7 citation statements)

References 11 publications

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“…Among malignancy associated intralymphatic histiocytosis, the most common observed tumor was breast cancer, with involvement presenting as erythematous patches developing on mastectomy scars . Other malignancies included colon carcinoma and melanoma . Korman et al reported a case very similar to our case.…”

Section: Characteristics Of Patients With Intralymphatic Histiocytosissupporting

confidence: 71%

“…Antibiotic therapy followed by tonsillectomy was also effective in the reported patient of with a 17‐year history of chronic tonsillitis . In a reported patient with colon cancer, complete resolution was noted after colonic surgery . With regard to RA, a 66‐year old woman with a 2 year history of a reddish brown plaque on her right elbow treated with 3 mg/kg of intravenous infliximab achieved a marked improvement in both her skin lesions and joint pain …”

Section: Characteristics Of Patients With Intralymphatic Histiocytosismentioning

confidence: 94%

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Intralymphatic Histiocytosis: A case report and review of literature

2015

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Section: Characteristics Of Patients With Intralymphatic Histiocytosissupporting

confidence: 71%

Section: Characteristics Of Patients With Intralymphatic Histiocytosismentioning

confidence: 94%

Intralymphatic Histiocytosis: A case report and review of literature

2015

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“…Intralymphatic histiocytosis, first described in 1994, is characterized by dilated vessels containing aggregates of mononuclear histiocytes in their lumina [1]. The majority of cases have been associated with RA [2] [3], although the condition has also been observed after the placement of metal implants and associated with malignant neoplasms [4]- [6]. The most commonly involved sites are the upper extremities, especially around the elbow joint and the lower extremities areoccasionally involved [7].…”

Section: Discussionmentioning

confidence: 99%

Intralymphatic Histiocytosis with Rheumatoid Arthritis: Possible Association with the Joint Involvement

Kaneko¹,

Takeuchi²,

Nakano³

et al. 2014

CRCM

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Intralymphatic histiocytosis is characterized by dilated vessels containing aggregates of mononuclear histiocytes in their lumina, and the majority of cases have been associated with rheumatoid arthritis (RA). We report a case of a 61-year-old woman with RA who presented with livedolike erythema and red papules around the right elbow and forearm. Histological examinations demonstrated numerous dilated vessels in the dermis partially filled with medium-to large-sized mononuclear cells. Immunohistochemically, most of the intraluminal cells were CD68-positive histiocytes. Endothelial cells were positive for D2-40, a marker for lymphatic endothelial cells. We diagnosed the patient with intralymphatic histiocytosis based on these clinical and histological findings. Interestingly, the skin manifestations exacerbated during the course of the disease when the swelling of the patient's right elbow joint progressed. Then, the puncture of content fluid of the joint was performed, since then, the symptoms of the skin lesion immediately improved. These observations suggest a possible association between the eruptions of intralymphatic histiocytosis and the involved joint. The results suggest that such skin eruptions may be ameliorated by treating severe arthritis.

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“…The disorder seems to be more common in women, and all cases have been reported in adult patients. The majority of cases have been found to be associated with rheumatoid arthritis, although it has also been observed after the placement of metal implants and associated with malignant neoplasms . Clinical lesions are characterized by asymptomatic, poorly demarcated, and irregular‐shaped, erythematous to brown plaques that show predilection for the extremities, near the involved joints.…”

Section: Discussionmentioning

confidence: 99%