Erythematous indurated plaque on the right upper limb

Bustos, Blanca de Unamuno; Rabasco, Ana García; Sánchez, Raúl; Aparicio, Antonio Martínez; Miquel, Víctor Alegre de

doi:10.1111/j.1365-4632.2012.05696.x

Cited by 16 publications

(6 citation statements)

References 14 publications

(15 reference statements)

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“…Treatment of intralymphatic histiocytosis is difficult, and a cure has not yet been established. It could be obvious spontaneously, or the treatment of the underlying condition may resolve intralymphatic histiocytosis 1,2,5 …”

Section: Discussionmentioning

confidence: 99%

Erythematous papule with serous discharge on an elbow

Park

Yoo

et al. 2022

Int J Dermatology

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Section: Discussionmentioning

confidence: 99%

Erythematous papule with serous discharge on an elbow

Park

Yoo

et al. 2022

Int J Dermatology

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“…However, this intriguing paper makes no reference to the possible pathogenic role of metal implants in such variants of IH. We think that metal implant‐associated IH may be considered the umpteenth unquestionable instance of the immunocompromised district (ICD) …”

mentioning

confidence: 97%

“…We read with great interest and enthusiasm the case report by de Unamuno Bustos et al ., published in the May issue of the International Journal of Dermatology . The Spanish authors described the case of a 74‐year‐old woman who developed an intralymphatic histiocytosis (IH) of the right upper limb two months after the placement of an orthopedic metal implant for a humerus fracture …”

mentioning

confidence: 99%

“…In the course of discussing the pathogenesis of this rare skin disorder, the authors refer to the different pathogenic proposals advanced before their observation. In particular, they stress that the pathogenesis of IH has still not been defined and that some authors speculate that IH may be an early stage of reactive angioendotheliomatosis, whereas others think it may result from the lymphatic drainage of histiocytes from the joints, particularly in subjects affected by rheumatoid arthritis …”

mentioning

confidence: 99%

“…In the case described by de Unamuno Bustos et al ., orthopedic surgery for placement of the metal implant would inevitably damage the lymphatic network, thus altering normal lymph drainage. This alteration of immune cell trafficking provokes an immune destabilization of the area served by interrupted or injured lymphatic vessels, making it prone to the development of opportunistic disorders, such as IH in this case.…”

mentioning

confidence: 99%

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A possible relationship between metal implant‐induced intralymphatic histiocytosis and the concept of the immunocompromised district

et al. 2014

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Two rare cases of laryngeal intralymphatic histiocytosis

Reznitsky

Daugaard

Charabi

2015

Eur Arch Otorhinolaryngol

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We report two rare cases of intralymphatic histiocytosis causing, respectively, recurrent and persistent episodes of upper airway swelling and breathing difficulties. Case 1 was a 39-year-old man who was referred with recurrent upper airway swelling causing difficulty in breathing. A direct laryngoscopy was performed under general anesthesia due to minimal effect from treatment with antibiotics and anti-oedema medication. On examination, the larynx was found to be swollen and oedematous but not inflamed. Biopsies from the aryepiglottic folds showed intralymphatic histiocytosis. The patient was extensively examined but the only abnormal finding was a low CD4 count. The breathing difficulties fluctuated during the diagnostic process and settled after a year. Case 2 was a 35-year-old man who presented with persistent laryngeal swelling. Biopsies from the epiglottis showed intralymphatic histiocytosis. Extensive investigations were performed but discovered no abnormal findings. He received CO2 laser treatment twice and the swelling decreased. Intralymphatic histiocytosis is extremely rare in upper airway pathology. It is an important differential diagnosis in patients with recurrent and chronic laryngeal swelling and dyspnoea.

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Erythematous indurated plaque on the right upper limb

Cited by 16 publications

References 14 publications

Erythematous papule with serous discharge on an elbow

Erythematous papule with serous discharge on an elbow

A possible relationship between metal implant‐induced intralymphatic histiocytosis and the concept of the immunocompromised district

Two rare cases of laryngeal intralymphatic histiocytosis

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