Intralymphatic Histiocytosis: A Report of 2 Cases

Sánchez, María Encarnación Gómez; Azaña-Defez, J.M.; Martínez-Martínez, M.L.; López-Villaescusa, María Teresa

doi:10.1016/j.adengl.2017.11.007

Cited by 5 publications

(11 citation statements)

References 14 publications

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“…Most cases are associated with rheumatoid arthritis (RA), although the clinical course of ILH does not correlate to its activity 2,3,4 . In our case, a positive rheumatoid factor without features of RA was observed; this finding is scarcely described in the reviewed literature 2 .…”

Section: Discussioncontrasting

confidence: 53%

“…Intralymphatic histiocytosis is a rare, benign, reactive cutaneous condition first described in 1994 1 . It is more common in adult and elderly women, and it predominantly arises on the proximal areas of the limbs 2,3 …”

Section: Discussionmentioning

confidence: 99%

“…Cases of ILH after orthopedic metal implant placement procedures such as hip and knee joint replacement and postfracture stabilization of the humerus have also been reported, thus constituting another triggering factor for its development 2,5 . In both RA and metal implant‐related cases, lesions of ILH arise in the vicinity of the affected joints 2,3,4 . There are anecdotal case reports related to breast, colon, and Merkel cell carcinoma surgery, malignant melanoma, axillary lymphadenectomy, or Crohn disease 3,4 .…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Erythemato‐violaceous plaque on the breast following implant replacement

Aranguren-López¹,

Arregui-Murua²,

Silva‐Soria³

2020

Int J Dermatology

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Section: Discussioncontrasting

confidence: 53%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Erythemato‐violaceous plaque on the breast following implant replacement

Aranguren-López¹,

Arregui-Murua²,

Silva‐Soria³

2020

Int J Dermatology

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“…rheumatoid arthritis), orthopedic implants, and even neoplastic lesions. 19 , 20 Most cases show cutaneous manifestations, but at least one visceral case has already been described. 21 …”

Section: Literature Reviewmentioning

confidence: 99%

Occurrence of mesothelial/monocytic incidental cardiac excrescences in material from open-heart procedures: case reports and literature review

et al. 2018

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Mesothelial/monocytic incidental cardiac excrescences (MICE) are unusual findings during the histological analysis of material from the pericardium, mediastinum, or other tissues collected in open-heart surgery. Despite their somewhat worrisome histological appearance, they show a benign clinical course, and further treatment is virtually never necessary. Hence, the importance of recognizing the entity relays in its differential diagnosis, as an unaware medical pathologist may misinterpret it for a malignant neoplasm. Other mesothelial and histiocytic proliferative lesions, sharing very close histological morphology and immunohistochemistry features with MICE, have been described in sites other than the heart or the mediastinum. This similarity has led to the proposal of the common denomination “histiocytosis with raisinoid nuclei.” We report three cases from the pathology archives of the Heart Institute of São Paulo University (Incor/HC-FMUSP), diagnosed as “mesothelial/monocytic incidental cardiac excrescence,” with immunohistochemical documentation, and provide a literature review of this entity.

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“…ILH frequently presents in patients with an underlying chronic disorder, predominantly inflammatory systemic disease or conditions in which local inflammation is a prominent component 2,3 . To date, published disease associations include rheumatoid arthritis, 2,6‐19 solid tumors, 2,20‐22 peripheral vascular disease, 5 and prior surgery, especially with metallic orthopedic implants 2,23‐29 . Some cases have been described with no known associated condition 3,28,30‐32 .…”

Section: Introductionmentioning

confidence: 99%

Intralymphatic histiocytosis in healing cellulitis: Case report and review of the literature

Goldsmith

Tahan

2020

J Cutan Pathol

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Intralymphatic histiocytosis (ILH) is a rare skin benign condition observed in a variety of inflammatory settings. It is characterized by the presence of ectatic dermal lymphatic vessels containing aggregates of histiocytes. Associated conditions that have been identified include rheumatoid arthritis, metallic orthopedic implants, inflammatory bowel disease, and malignancies of the breast, skin, and colon. Some cases with no attributable underlying cause have been described. The pathophysiology of ILH is not well understood. It has been proposed that it may represent macrophage migration during immune activation. Herein, we present the first description of ILH observed in the healing phase of cellulitis on the skin of the breast. Awareness of this possibility is important when the diagnosis of intravascular carcinomatosis is being considered.

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Intralymphatic Histiocytosis: A Report of 2 Cases

Cited by 5 publications

References 14 publications

Erythemato‐violaceous plaque on the breast following implant replacement

Erythemato‐violaceous plaque on the breast following implant replacement

Occurrence of mesothelial/monocytic incidental cardiac excrescences in material from open-heart procedures: case reports and literature review

Intralymphatic histiocytosis in healing cellulitis: Case report and review of the literature

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