Intragastric balloon for treatment-resistant obesity: safety, tolerance, and efficacy of 1-year balloon treatment followed by a 1-year balloon-free follow-up

Mathus-Vliegen, Elisabeth M. H.; Tytgat, G. N. J.

doi:10.1016/s0016-5107(04)02406-x

Cited by 200 publications

(196 citation statements)

References 18 publications

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“…The majority of these studies have been uncontrolled and/or retrospective (13)(14)(15)(16)(17)(18)(19)(20). Only three studies published to date employed a prospective, randomized, controlled trial design with a long-term follow-up (!1 year) (21-23); two of which included the use of more than one IGB (21,22). Regardless as to the study design, a mean weight loss of 10% was maintained for up to one year after IGB removal in those studies with an extended post-removal follow-up period (16,21,24).…”

Section: Introductionmentioning

confidence: 99%

An intragastric balloon in the treatment of obese individuals with metabolic syndrome: A randomized controlled study

Fuller

Pearson

Lau

et al. 2013

Obesity

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Objective: There are limited controlled data for intragastric balloons (IGB) in obesity treatment. This randomized, controlled study evaluated the efficacy and safety of an IGB in obese individuals with metabolic syndrome (MS). Design and Methods: Sixty-six adults (BMI: 30-40 kg/m 2 ) were randomized to IGB for 6 months, with a 12 month behavioral modification (IGB Group; ''IGBG''), or 12 month behavioral modification alone (Control Group; ''CG''). The primary outcome was percentage change in body weight. Results: Thirty-one subjects (female: 68%; mean age: 43; mean BMI: 36.0) were randomized to IGBG and 35 (66%; 48; 36.7) to CG. At 6 months, there was a significantly greater weight loss in the IGBG: À14.2 vs. À4.8; P < 0.0001. This was associated with a significantly greater reduction in waist circumference, and an improvement in quality of life, with a trend for a larger %MS remission (50% vs. 30%; n.s.). At month 12, the differences in weight loss were enduring: À9.2 vs. À5.2; P ¼ 0.007. Gastrointestinal-related adverse events were common in the IGBG, resolving predominantly within two weeks. The IGB was removed prematurely in three subjects (one for refractory gastrointestinal symptoms). Conclusions: Statistically significant and clinically relevant improvements in weight loss and health outcomes were observed with the IGBG at 6 months versus behavioral modification alone. The differential weight loss was still evident 6 months after IGB removal.

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Section: Introductionmentioning

confidence: 99%

An intragastric balloon in the treatment of obese individuals with metabolic syndrome: A randomized controlled study

Fuller

Pearson

Lau

et al. 2013

Obesity

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“…Significant associations have been reported between BMI and age with periodontitis (25), and obesity has been reported to be associated with dental caries and periodontitis (26).…”

Section: Discussionmentioning

confidence: 99%

The Correlation Between Body Mass Index and Oral Health in 12-Year-Old Students in Tehran During 2011

Nakhostin¹,

Meighani²,

Abbasi³

et al. 2016

Avicenna J Dent Res

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Background: The growing prevalence of being overweight and obesity in children has raised significant public health concerns. Obesity is considered a risk factor for several chronic health conditions and is associated with increased mortality. In addition, recent studies have shown an association between obesity and periodontal disease. Objectives: The present study sought to assess the correlation of body mass index (BMI) with periodontal disease. Materials and Methods: A total of 1,024 12-year-old elementary school students were selected by cluster sampling from five regions of Tehran. BMI was used as a measure of being overweight and obesity, and the oral hygiene index (OHI) was used to assess periodontal disease. A linear regression model was applied to estimate the association between BMI and OHI. The parents' level of education and family income were also evaluated.

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“…Due to this fact, and as the greatest weight loss occurs within the Wrst 3 months [15], endoscopic removal after 6 months is highly recommended. In our case, however, the balloon had been left in place for more than 3 years.…”

Section: Discussionmentioning

confidence: 99%

Parastomal hernia incarceration due to migrated intragastric balloon

Limani

Steinemann

Clavien

et al. 2011

Hernia

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The temporary placement of intragastric balloons is a common method to achieve rapid weight loss before planned metabolic surgery. We report the case of a 48-year-old morbidly obese patient. Ten years ago the patient underwent emergency sigmoidectomy with creation of a double-barreled ileostomy for perforated diverticulitis. Over time he developed a giant parastomal hernia. For preoperative weight reduction before planned restoration of intestinal continuity, an intragastric balloon was inserted 3 years ago. The patient was admitted to our emergency department with peritonism and a septic shock. After computed tomography showing small bowel ileus, laparotomy was performed, revealing marked ischemia of incarcerated small and large intestine. Only postoperatively was the intragastric balloon found in the resected small bowel, causing a mechanical ileus with consecutive incarceration of the bowel. We review the literature on complications due to the migration of intragastric balloons. This clinical case gives a fair warning of the possible deleterious outcome of intragastric balloons, especially in hernia patients.

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Intragastric balloon for treatment-resistant obesity: safety, tolerance, and efficacy of 1-year balloon treatment followed by a 1-year balloon-free follow-up

Cited by 200 publications

References 18 publications

An intragastric balloon in the treatment of obese individuals with metabolic syndrome: A randomized controlled study

An intragastric balloon in the treatment of obese individuals with metabolic syndrome: A randomized controlled study

The Correlation Between Body Mass Index and Oral Health in 12-Year-Old Students in Tehran During 2011

Parastomal hernia incarceration due to migrated intragastric balloon

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