Intraductal Ultrasonography May Localize Islet Cell Tumours Negative on Endoscopic Ultrasound

Menzel, J.; Domschke, Wolfram

doi:10.1080/00365529850166301

Cited by 33 publications

(3 citation statements)

References 11 publications

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“…Either enucleation or distal pancreatectomy is used for lesions located in body or tail of the pancreas; enucleation is indicated for small, benign lesions located at least 2–3 mm from the main pancreatic duct [7]. Intraoperative ultrasonography and intraductal ultrasonography can be used to measure the distance between tumor margin and main pancreatic duct [15,16,17]. In our study, open surgery was performed in 21 patients with tumors located in body or tail of the pancreas: 14 enucleations and 7 distal resections.…”

Section: Discussionmentioning

confidence: 99%

Strategy for the Surgical Management of Insulinomas: Analysis of 52 Cases

Liu¹,

Peng

Zhang

et al. 2007

Dig Surg

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Aim: The goal of this retrospective study was to analyze the strategy for the surgical management of insulinomas. Methods: From May 2000 to October 2006, the medical records of 52 patients with insulinomas were retrospectively studied. Results: All tumors were localized precisely by imaging techniques combined with intraoperative palpation. Forty-eight patients with benign lesions underwent surgical treatment: 41 patients open and 7 patients laparoscopic procedures. Four patients with malignant insulinomas underwent tumor resection; 3 of them underwent metastatic lesion and/or lymph node dissection. There were no discrepancies regarding operation time, blood loss, and complication rate between open enucleation and laparoscopic surgery. The mean hospital stay was 11.8 ± 3.4 days after laparoscopic surgery, shorter than the 17.0 ± 6.0 days after the open approach. Twenty-two complications occurred in 17 patients (32%) following resection. On follow-up, 86% of the patients were free from symptoms, and surgical cure was achieved in 95% of the patients with benign insulinomas. Conclusions: The choice of the surgical strategy for the treatment of pancreatic insulinomas depends on size and location of the tumor and the risk of malignancy. The optimal surgical procedure is key to prevent postoperative complications. The laparoscopic approach is safe and feasible for patients with benign tumors located in body or tail of the pancreas.

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Section: Discussionmentioning

confidence: 99%

Strategy for the Surgical Management of Insulinomas: Analysis of 52 Cases

Liu¹,

Peng

Zhang

et al. 2007

Dig Surg

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“…Intraductal ultrasound (IDUS) utilizes miniprobes that can be passed directly into pancreatic and bile ducts through a standard endoscope. IDUS has been most often used in the diagnosis and investigation of biliary disease; however, there is limited data to suggest IDUS may be an alternative diagnostic modality for PNETs [ 30 , 31 ]. In one study, three patients with presumed PNETs underwent several imaging modalities, including endoscopic ultrasound, without tumor localization.…”

Section: Presentation and Diagnosis Of Pancreatic Neuroendocrine Tumorsmentioning

confidence: 99%

“…In one study, three patients with presumed PNETs underwent several imaging modalities, including endoscopic ultrasound, without tumor localization. All patients were found to have PNETs less than 2 cm and were detected by IDUS [ 30 ].…”

Section: Presentation and Diagnosis Of Pancreatic Neuroendocrine Tumorsmentioning

confidence: 99%

Surgical Management of Pancreatic Neuroendocrine Tumors

Sulciner

Clancy

2023

Cancers

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Pancreatic neuroendocrine tumors (PNETs) are relatively uncommon malignancies, characterized as either functional or nonfunctional secondary to their secretion of biologically active hormones. A wide range of clinical behavior can be seen, with the primary prognostic indicator being tumor grade as defined by the Ki67 proliferation index and mitotic index. Surgery is the primary treatment modality for PNETs. While functional PNETs should undergo resection for symptom control as well as potential curative intent, nonfunctional PNETs are increasingly managed nonoperatively. There is increasing data to suggest small, nonfunctional PNETs (less than 2 cm) are appropriate follow with nonoperative active surveillance. Evidence supports surgical management of metastatic disease if possible, and occasionally even surgical management of the primary tumor in the setting of widespread metastases. In this review, we highlight the evolving surgical management of local and metastatic PNETs.

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The management of insulinoma

Tucker¹,

Crotty²,

Conlon³

2006

British Journal of Surgery

177

140

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Most insulinomas are intrapancreatic, benign and solitary. Biochemical diagnosis is obtained during a supervised 72-h fast. Non-invasive preoperative imaging techniques to localize lesions continue to evolve. Intraoperative ultrasonography can be combined with other preoperative imaging modalities to improve tumour detection. Surgical resection is the treatment of choice. In the absence of preoperative localization and intraoperative detection of an insulinoma, blind pancreatic resection is not recommended.

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Intraductal Ultrasonography May Localize Islet Cell Tumours Negative on Endoscopic Ultrasound

Cited by 33 publications

References 11 publications

Strategy for the Surgical Management of Insulinomas: Analysis of 52 Cases

Strategy for the Surgical Management of Insulinomas: Analysis of 52 Cases

Surgical Management of Pancreatic Neuroendocrine Tumors

The management of insulinoma

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