Intracystic Primary Squamous Cell Carcinoma of the Breast: A Challenging Diagnosis

Ramos, V.; Fraga, Jorge Gerardo Pereira; Simões, Tomás; Figueiredo-Dias, Margarida

doi:10.1155/2016/6081634

Cited by 5 publications

(4 citation statements)

References 19 publications

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“…Primary SCC of the breast is a rare tumour, accounting for an estimated frequency of 0.1-3.6% of all invasive breast cancers with poor clinical outcomes [9][10][11]. Skin or nipple cancer and metastasis sites should be excluded when SCC is diagnosed [12]. The clinical symptoms of implant-associated SCC are likely to be a primary mammary tumour, and the histological appearance is important to make the diagnosis [13,14].…”

Section: Discussionmentioning

confidence: 99%

Breast prosthetic implant-associated Squamous Cell Carcinoma: A case report and Literature Review

Liu

Zhao

et al. 2021

Preprint

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BackgroundBreast reconstruction is widely used for women undergoing mastectomy. Prosthetic implants have become a common technique performed for these women because of their safety, flexibility and adjustable size. There are few reports of implant-associated squamous cell carcinoma. In addition to this report, only 8 reports including 11 cases have been reported in the English literature.Case presentationWe report the case of a patient with breast prosthetic implant-associated squamous cell carcinoma who received mastectomy and prosthetic implants 10 years ago. She was recently hospitalized with unilateral breast enlargement. Surgical pathology showed squamous cell carcinoma around the breast implant. There was no evidence of primary squamous cell carcinoma at any other anatomic site. We analysed all 11 patients with breast implant-derived squamous cell carcinoma (SCC) from a thorough literature search to identify studies. The median age of patients at SCC diagnosis was 56.8 years old. The average time from initial breast augmentation until SCC diagnosis was 21.9 years. The prognosis was poor; 4 of the 11 patients eventually progressed or died within 1 year, 3 of the 11 patients were disease free during the follow-up period, and 4 of the 11 patients were lost to follow-up. The most widespread opinion is that chronic inflammation from breast implants plays a substantial role in the disease progression of SCC.ConclusionsWe reported the rare complications associated with breast prosthetic implants and reviewed the literature. This malignancy should be taken into account in patients with breast prosthetic implants who have acute breast pain and enlargement.

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Section: Discussionmentioning

confidence: 99%

Breast prosthetic implant-associated Squamous Cell Carcinoma: A case report and Literature Review

Liu

Zhao

et al. 2021

Preprint

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“…The neoplastic cells infiltrate the adjacent stroma and an increase in size occurs on follow-up. Among the reported cases of squamous cell carcinoma of the breast, the diagnosis using FNAS was different: benignity or malignancy [11,12]. This difference was caused by the difficultly in the evaluation of the atypia of squamous epithelium, and so if RCBM is used for such tumors, it provides a precise evaluation of the atypical status of squamous epithelium and relationship between the atypical epithelium and stroma, leading to a precise diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Combined Core Needle Biopsy and Fine Needle Aspiration Cytology Using Returned Cell Block Method is Effective for Diagnosis of Cystic Lesions of the Breast

Kosaka¹,

Azami²,

Iino³

et al. 2017

J Cytol Histol

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Background: Core needle biopsy (CNB) and fine needle aspiration cytology (FNAC) are useful methods to diagnose cystic lesions of the breast. The first English article describing the returned cell block method (RCBM: cell block from a Papanicolaou staining smear on a glass slide) was reported by us, and we also reported the usefulness of RCBM for the FNAC-based evaluation of tumors of the breast. In the present study, diagnostic procedures of CNB and FNAC using RCBM for cystic lesions of the breast were studied.

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“…Breast cyst is a kind of common benign lesions of breast, which is one of the most common breast lumps in women with breast cancer, 75 and about 10% of women will develop cysts. 76 It is most common between the ages of 35 and 50, especially during menopause. 77,78 It includes simple breast cyst and product breast cyst.…”

Section: Breast Cystmentioning

confidence: 99%

Multiphoton microscopy for monitoring the occurrence, metastasis and therapy of breast cancer

Liu

et al. 2021

Micro & Optical Tech Letters

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Worldwide, the most common malignancy in women is breast cancer. At present, the gold standard for breast cancer diagnosis, namely pathological analysis, cannot reach the subcellular level, and is unable to provide more physiological information. Multiphoton microscopy (MPM) has its unique advantages, such as label‐free detection, high resolution, low damage, deep imaging depth, low photobleaching and phototoxicity, and so on, which make up for the deficiences of traditional methods. This review mainly introduces the principle of MPM and its applications in breast diseases, especially in monitoring the occurrence, progression, metastasis, and therapy response of tumor. At the same time, the performance and progress of MPM combined with nanomaterials in breast cancer treatment are summarized. Finally, we propose the clinical challenges and future research directions of MPM.

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Intracystic Primary Squamous Cell Carcinoma of the Breast: A Challenging Diagnosis

Cited by 5 publications

References 19 publications

Breast prosthetic implant-associated Squamous Cell Carcinoma: A case report and Literature Review

Breast prosthetic implant-associated Squamous Cell Carcinoma: A case report and Literature Review

Combined Core Needle Biopsy and Fine Needle Aspiration Cytology Using Returned Cell Block Method is Effective for Diagnosis of Cystic Lesions of the Breast

Multiphoton microscopy for monitoring the occurrence, metastasis and therapy of breast cancer

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