Intracranial Relapse of Nasopharyngeal Carcinoma Manifested as Sudden Deafness

Abstract

Magnetic resonance imaging should be performed to exclude intracranial relapse if sudden deafness develops in a patient with NPC within 5 years after irradiation.

Cochlear Implantation in Postirradiated Ears: Outcomes and Challenges

“…In patients who had been treated for malignancy, magnetic resonance imaging scans are frequently used to exclude the possibility of tumor recurrence. In the workup of a previously treated patient with NPC presenting with deteriorating deafness, magnetic resonance imaging is essential to exclude tumor recurrence involving the cerebellopontine angle 6 (case no. 3).…”

Effect of irradiation on vestibular evoked myogenic potentials in nasopharyngeal carcinoma survivors

“…Because more and more long-term NPC survivors developed postirradiation dizziness, 23 if accompanied by delayed VEMPs, one may attribute it to the radiation-induced otitis media or brainstem lesion. Hence, VEMP testing may expand the test battery for clinicians to explore balance problems in NPC survivors after irradiation.…”

Irradiated ears in nasopharyngeal carcinoma survivors: A review

“…The mean interval between completion of radiotherapy and onset of acute hearing loss is > 10 years for PISD. In contrast, acute hearing loss that occurs < 5 years after irradiation may indicate tumor relapse . Further, newly developed multiple cranial nerve deficits provide another clue to differentiate intracranial tumor relapse from PISD.…”