Intracranial Invasion From Recurrent Angiosarcoma of The Scalp

Choi, Kyu-Sun; Chun, Hyung-Joon; Yi, Hyeong-Joong; Kim, Jeong-Tae

doi:10.3340/jkns.2008.43.4.201

Cited by 4 publications

(2 citation statements)

References 13 publications

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“…Scalp angiosarcoma causing brain metastasis is an extremely rare and lethal disease. Kyu-Sun et al and Ellegala et al reported two case of angiosarcoma brain metastases arising from the scalp 18 , 19. Our case illustrates probable scalp angiosarcoma primary with brain metastases as an unusual clinical conundrum and highlights a difficulty, rarely reported, in distinguishing between brain haemorrhage and brain angiosarcomata.…”

Section: Discussionmentioning

confidence: 54%

Metastatic angiosarcoma: a vascular tumour or an intracranial haemorrhage?

Masih

McIlwaine²

2010

Case Reports

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A 64-year-old man presented with weakness of his right arm and leg. He had previously had mitral valve replacement, tricuspid annuloplasty, leg deep vein thrombosis (DVT) and femoral embolism. Computed tomography (CT) scan of the brain showed an acute left thalamic haemorrhage. Repeat CT brain showed resolution of the original haemorrhage, but the apparent development of new areas of haemorrhage. Warfarin continued due to high risk of thromboembolism. He was readmitted with the rapid development of a visible swelling at the sternum and on the scalp. Ultrasound scan of the sternum revealed a vascular tumour. Suspected haemorrhages in the past were reported as the metastatic deposits. Biopsy and immunohistochemical staining confirmed angiosarcoma of the scalp. Being vascular tumours, angiosarcoma can mimic a brain haemorrhage. Our case illustrates a clinical conundrum. Diagnosing metastatic angiosarcoma of the brain proved difficult without visible primary and histology. The rapid clinical course of the disease and problems with anticoagulation therapy made treatment options limited and the prognosis worse.

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Section: Discussionmentioning

confidence: 54%

Metastatic angiosarcoma: a vascular tumour or an intracranial haemorrhage?

Masih

McIlwaine²

2010

Case Reports

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“…Angiosarcoma of the scalp has a predilection for pulmonary metastasis (10), and it appears to be a naturally privileged barrier that hinders local spread and resultant seeding in the cranial cavity, thus angiosarcoma metastasizing to the brain is relatively rare (11,12). In the present study, metastases of the lung and brain occurred at the time of diagnosis.…”

Section: Discussionmentioning

confidence: 71%

Diffuse alveolar hemorrhage due to metastatic angiosarcoma of the lung: A case report

Pan

Zhou

et al. 2015

Oncology Letters

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Abstract. Angiosarcoma is a rare, heterogeneous malignant tumor that derives from endothelial cells, and it has aggressive characteristics with a marked tendency for distant metastasis. Diffuse alveolar hemorrhage (DAH) is a catastrophic clinical syndrome, however, it is rare as the presentation of pulmonary angiosarcoma. To increase awareness with regard to angiosarcoma and DAH, the current study presents a case of angiosarcoma that originated from the subcutaneous soft tissue of the mastoid process, but was subject to a delayed diagnosis and rapid invasion into the brain and lung. The metastatic angiosarcoma of the lung presented with DAH as the initial manifestation. The pathological examination of a biopsy of the subcutaneous mass and pulmonary lesions confirmed the diagnosis of angiosarcoma. The patient succumbed to respiratory failure at 1 month post-diagnosis.

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