1982
DOI: 10.1177/030098588201900608
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Intracranial Epidermoid Cysts in Three Dogs

Abstract: Abstract. Intracranial epidermoid cysts were identified within the fourth ventricle of three dogs. The cysts measured up to 2.5 cm in diameter, were lined by stratified squamous epithelium, and contained intraluminal keratinaceous debris. Secondary compression of the medulla oblongata and cerebellum caused neurologic dysfunction in two dogs; the cyst was an incidental finding in the other dog. Similarities between these dogs and three previously reported intracranial epidermoid cysts in dogs included an appare… Show more

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Cited by 33 publications
(39 citation statements)
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“…33 There are sporadic case reports of affected dogs that represent postmortem findings and only occasionally include attempted therapy. [34][35][36][37][38][39][40][41] Most of the intracranial canine epidermoid cysts reported have been located in the cerebellopontine/medullary angle, and can extend into the fourth ventricle 34,35,[37][38][39][40][41][42] (Fig. 2).…”
Section: Epidermoid Cystsmentioning
confidence: 99%
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“…33 There are sporadic case reports of affected dogs that represent postmortem findings and only occasionally include attempted therapy. [34][35][36][37][38][39][40][41] Most of the intracranial canine epidermoid cysts reported have been located in the cerebellopontine/medullary angle, and can extend into the fourth ventricle 34,35,[37][38][39][40][41][42] (Fig. 2).…”
Section: Epidermoid Cystsmentioning
confidence: 99%
“…34 The stratified squamous epithelium lining of epidermal cysts is believed to undergo progressive exfoliation leading to an accumulation of keratinized material, cholesterol clefts, and some inflammatory cells in the lumen and subsequent expansion of the cyst. 2,42,43 The lining of the epidermoid cyst helps differentiate these structures from dermoid cysts, which have a more complex arrangement of dermis that may include hair follicles, sebaceous glands, and sweat glands. 2,37,42 Clinical Signs Neurologic signs were not reported in several dogs with central nervous system epidermoid cysts; the cyst was an incidental finding on postmortem examination 38,40,42 ; because the cysts show slow, linear growth, neurologic signs often present in middle age in humans and dogs.…”
Section: Pathophysiologymentioning
confidence: 99%
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“…The occurrence of intracranial epidermoid cysts is rare in dogs, and only 6 cases have been reported in the literature (McGrath, 1960;Mawdesley-Thomas & Hague, 1970;Zaki, 1977;Kornegay & Gorgacz, 1982). The condition is usually unilocular, and no further variant has been documented.…”
mentioning
confidence: 99%
“…Epidermoid cysts in the CNS have been reported in various species such as the mouse (7,9,10), rat (7,11,12), dog (4,6,9), lamb (1), horse (5), and human (2,3). According to a previous description, the rodent epidermoid cyst is lined by strati ed squamous epithelium and lled with desquamated keratin (7,9,10,12).…”
mentioning
confidence: 99%