Intrachiasmatic abscess caused by IgG4-related hypophysitis

Abstract

This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.

Pituitary Abscess as Manifestation of IgG4-Related Hypophysitis: A Case Report

“…However-as in the current case-patients typically present with no fever, no leukocytosis, and culture results are negative. Notably, abscess is an extremely rare manifestation of IgG4-related hypophysitis, as only one case has been reported to our knowledge to date [16]. In the current case, both clinically and radiologically the pituitary lesion was compatible with an abscess: during the surgeries, yellowish purulent material was drained from the pituitary lesion (in fact, the initial clinical orientation was a pyogenic abscess or an abscess formation in pituitary adenoma) and on imaging studies the lesion showed well-defined irregular borders with peripheral enhancement after the administration of intravenous contrast material, exerting mass effect of adjacent structures.…”

Immunoglobulin G4 hypophysitis in a 63-year-old woman with no autoimmune history: a case report

“…Most recently, there have been adjunctive postoperative biologic treatments that have been attempted. Corticosteroids were given in all cases; additionally, two patients received rituximab [ 3 ], one patient received azathioprine [ 4 ], and one patient received mycophenolate mofetil [ 11 ]. No death occurred in the cases presented [ 29 ]; however, there has been no comment in the literature about any residual deficits after treatment.…”