Intracerebral regional distribution of blood flow in response to uterine contractions in growth-restricted human fetuses

Middle versus anterior cerebral artery Doppler for the prediction of perinatal outcome and neonatal neurobehavior in term small‐for‐gestational‐age fetuses with normal umbilical artery Doppler

“…For those delivering beyond that gestational age MCA‐PI and ACA‐PI showed a similar association with perinatal outcome. Also in line with this reasoning, other studies have found no differences between ACA and MCA in response to acute hypoxia in term SGA fetuses24. As a secondary explanation, the considerable degree of systemic fetal hemodynamic adaptation to hypoxia in early‐onset IUGR, which is not present in term SGA, could also influence brain hemodynamics in ways that we cannot interpret.…”

Are fetuses that fail to achieve their growth potential at increased risk of intrapartum compromise?

“…It has been suggested that alterations in cerebral and umbilical blood flow associated with FGR are an adaptive response to suboptimal placental function, occurring prior to subsequent deterioration in growth velocity. Furthermore, in the presence of uterine contractions, growth‐restricted fetuses undergo further acute cerebral redistribution.…”

Normal Doppler Reference Values of the Pericallosal Artery

“…A functional impairment of the basal ganglia will result in a variety of dysfunctions among which motor dysfunctions are the most obvious. Involvement of the internal capsule will result in interrupted cortico-subcortical connections [18]. The ACA supplies the antero-medial cerebral cortex, from the frontal lobe to the parietal lobe all the way to the sulcus parietooccipitalis.…”