Intracardiac surgery in infants under age 3 months: Incremental risk factors for hospital mortality

Kirklin, James K.; Blackstone, Eugene H.; Kirklin, John W.; McKay, Roxane; Pacifico, Albert D.; Bargeron, Lionel M.

doi:10.1016/0002-9149(81)90079-5

Cited by 122 publications

(37 citation statements)

References 13 publications

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“…Previous reports have suggested that low weight and premature age are risk factors for poor outcome after correction of congenital heart defects [2,3]. Additionally, the perception that these premature infants are more vulnerable by associated issues such as immature lungs and the potential risk for cerebral hemorrhage, has supported the belief of many neonatologists that corrective surgery with the use of cardiopulmonary bypass has to be avoided in favor of a supportive medical therapy or surgical palliation.…”

Section: Commentmentioning

confidence: 99%

Outcome analysis of major cardiac operations in low weight neonates

Bové

François

Groote

et al. 2004

The Annals of Thoracic Surgery

101

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secutive neonates of less than 2,500 g underwent early surgery for congenital heart disease. A retrospective analysis was performed to evaluate the early to medium term outcome.Methods. Major cardiac surgery for congenital heart defects included a complete correction in 31 patients (group I) and a palliative procedure in 18 patients (group II). Mean age at operation was 15.2 days (1 day-90 days) and mean weight was 2,190 g (1,300 g-2,500 g). Twentyfour children (49%) were born prematurely. All neonates were critically ill and 47% were already ventilated preoperatively. Heart defects included mainly ventricular septal defect (10), tetralogy of Fallot complexes (8), aortic coarctation (8), transposition complexes (7), single ventricle anomalies (4), pulmonary atresia with intact septum (4), interrupted aortic arch (3), totally anomalous pulmonary venous return (3), and common atrioventricular septal defect (2).Results. Overall surgical mortality was 18%: 4 neonates died after definitive repair and 5 after palliation; repre-

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Section: Commentmentioning

confidence: 99%

Outcome analysis of major cardiac operations in low weight neonates

Bové

François

Groote

et al. 2004

The Annals of Thoracic Surgery

101

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“…Kirklin ve ark. [17] yaptıkları çalışmada pulmoner venöz obstrüksiyon ve klinik durumun kötü olmasını en önemli risk olarak bildirmişler-dir. Günümüzde TPVDA renkli-dopler ekokardiyografinin yardımı ile transtorasik ekokardiyografi ile tanı konulabilir [18].…”

Section: Discussionunclassified

Surgical Outcome of Total Anomalous Pulmonary Venous Return; Single Center Experience

Kırbaş¹,

Yalçın²,

Tanrikulu³

et al. 2013

Ann Clin Anal Med

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“…However, clinically the hearts of children are more vulnerable to ischemia, in spite of the use of cardioplegia, when compared to adults [1,14].…”

Section: Commentsmentioning

confidence: 99%

“…KIRKLIN et al [14] emphasized the importance of the influence of congestive heart disease in the pre-operative period, interfering in the evolution after corrective surgery. It is possible to see in this study, using univariant analysis, that congestive heart failure in the pre-operative period had an influence on the peak of troponin I and CK-MB mass.…”

Section: Commentsmentioning

confidence: 99%

The behavior of Troponin I and CKMB mass in children who underwent surgical correction of congenital heart malformations

Salerno¹,

Jatene²,

Figueiredo³

et al. 2003

Rev Bras Cir Cardiovasc

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Objective: To analyze the behavior of troponin (TROP I) and CKMB mass (CKMBm) in regards to the addition of magnesium in cardioplegic solutions; and also the influence of per-operative factors.Method: A total of 28 children with ages ranging from 3 to 108 months were studied. The mean weight was 11.8 kg. Eighteen were male. The patients were divided into two groups. Sixteen children in group I (GI) and 12 in group II (GII). The patients in GI received cold blood cardioplegic solution with magnesium (12 mEq/L) and potassium chloride (20 mEq/L) at 20 mL/kg. The patients in GII received the same solution without magnesium. Six blood samples were collected for serum analysis of the concentration of TROP I and CKMBm. The blood samples were collected before clamping the aorta and at 1, 6, 24, 48 and 72 hours after aorta clamping termination.Results: There were no statistical differences in the TROP I and CKMBm levels between the two groups. Among the per-operative factors cyanosis influenced the TROP I and CKMBm levels. Additionally, the aorta clamping time influenced the TROP I levels.Conclusions: The addition of magnesium in the cardioplegic solution was not associated with different levels of TROP I and CKMBm. Cyanosis and aorta clamping time interfered with peak TROP I levels.Descriptors: Troponin I, blood. Creatine kinase, blood. Heart defects, congenital, surgery. Magnesium sulfate, therapeutic use. Cardioplegic solutions, chemistry. Cardiovasc 2003; 18(3): 235-241 Rev Bras Cir

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Intracardiac surgery in infants under age 3 months: Incremental risk factors for hospital mortality

Cited by 122 publications

References 13 publications

Outcome analysis of major cardiac operations in low weight neonates

Outcome analysis of major cardiac operations in low weight neonates

Surgical Outcome of Total Anomalous Pulmonary Venous Return; Single Center Experience

The behavior of Troponin I and CKMB mass in children who underwent surgical correction of congenital heart malformations

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