Outcome analysis of major cardiac operations in low weight neonates

Abstract

secutive neonates of less than 2,500 g underwent early surgery for congenital heart disease. A retrospective analysis was performed to evaluate the early to medium term outcome.Methods. Major cardiac surgery for congenital heart defects included a complete correction in 31 patients (group I) and a palliative procedure in 18 patients (group II). Mean age at operation was 15.2 days (1 day-90 days) and mean weight was 2,190 g (1,300 g-2,500 g). Twentyfour children (49%) were born prematurely. All neonates were critically ill and 47% were already ventilated preoperatively. Heart defects included mainly ventricular septal defect (10), tetralogy of Fallot complexes (8), aortic coarctation (8), transposition complexes (7), single ventricle anomalies (4), pulmonary atresia with intact septum (4), interrupted aortic arch (3), totally anomalous pulmonary venous return (3), and common atrioventricular septal defect (2).Results. Overall surgical mortality was 18%: 4 neonates died after definitive repair and 5 after palliation; repre-

Perfil de recém-nascidos submetidos à cirurgia cardíaca em hospital privado do Município de São Paulo

“…A idade gestacional e o baixo peso ao nascer são aspectos relevantes na abordagem ao RN cardiopata, consideradas como fatores de risco para avaliar o comprometimento neurológico e associadas à maior taxa de mortalidade precoce no PO (12)(13) .…”

“…Importante ressaltar que o restabelecimento, ainda no período neonatal, da função cardiovascular por meio de intervenção cirúrgica, promove efeitos benéficos na maturação de órgãos como os pulmões, o cérebro e o próprio coração (12) .…”

The effect of late preterm birth on mortality of infants with major congenital heart defects

“…7 Other reports of outcome of infants with CHDs described actuarial survival 3 or infant mortality. 1,8 Our report focuses on the effect of birth at the narrower range of late preterm gestational ages (34 to 36 weeks), a cohort that is increasingly identified as an at-risk population. This report also provides outcomes representative of a more current era of neonatal care (2002 to 2009).…”

Growth in Congenital Heart Disease: Outcome or Predictor?

“…In the era of personalized medicine, premature and small neonates should not be considered a homogeneous high‐risk category. Although prematurity (<37 weeks’ gestation) and low birth weight (<2.5 kg) increase risk1, 2, 3, 4 on a population basis, the individual preterm or small infant may actually do well. Extrapolating risk from the outcomes of a diverse cohort to an individual is unreliable and potentially misleading, whether it be for counseling a family or discovering novel interventions to improve outcomes.…”