2014
DOI: 10.1016/j.ygyno.2014.03.569
|View full text |Cite
|
Sign up to set email alerts
|

Intra-operative frozen section results reliably predict final pathology in endometrial cancer

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2

Citation Types

3
40
0
3

Year Published

2014
2014
2023
2023

Publication Types

Select...
6
3

Relationship

0
9

Authors

Journals

citations
Cited by 67 publications
(54 citation statements)
references
References 46 publications
3
40
0
3
Order By: Relevance
“…Therefore, frozen section analysis has been widely adopted as a one-stop method of risk-stratification. Although the assessment of lymphovascular space invasion and cervical stromal involvement may not be possible or feasible by frozen section, the risk for lymph node metastasis can be reliably estimated by other features of the primary tumor, at least at institutions where sample flow is high enough for the development of an appropriate pathology expertise [21,22]. At institutions with less experience on the method, frozen section may have a poorer correlation with final pathology [23][24][25].…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, frozen section analysis has been widely adopted as a one-stop method of risk-stratification. Although the assessment of lymphovascular space invasion and cervical stromal involvement may not be possible or feasible by frozen section, the risk for lymph node metastasis can be reliably estimated by other features of the primary tumor, at least at institutions where sample flow is high enough for the development of an appropriate pathology expertise [21,22]. At institutions with less experience on the method, frozen section may have a poorer correlation with final pathology [23][24][25].…”
Section: Discussionmentioning
confidence: 99%
“…Intraoperative FS, to its advantage, assesses all high-risk criteria (including tumor size, histological subtype, histological grade, and depth of MI) with reasonably high diagnostic performance. 20 Researchers from the Mayo Clinic, where systematic use of FS in the intraoperative setting was pioneered, reported in a prospective analysis discrepancy rates as low as 7% between the FS and permanent section results of 784 patients with EC. 21 This discordance rate in histological subtype, histological grade, and MI translated into a clinically significant change in only 1.3% of patients, illustrating that FS may be the most reliable technique for intraoperative decision-making in institutions with a robust intraoperative consultation system.…”
Section: Discussionmentioning
confidence: 99%
“…В 2014 году была предложена новая классификация гиперплазии эндомет-рия, которая включила не только ранее описанные катего-рии (EIN), но и результаты генетических исследований, что позволило рассматривать патологию в свете современного понимания молекулярно-генетических механизмов фор-мирования новообразований эндометрия [12,20]. Выделе-ние только двух категорий ГЭ (без атипии и с атипией) зна-чительно упростит терминологию и понимание проблемы для клинициста (табл.…”
Section: Introductionunclassified
“…Для своевременного выявления и правильной клиниче-ской интерпретации морфологических изменений эндо-метрия, а также установления их гормонозависимости и адекватного дифференцированного лечения гиперплас-тического процесса чрезвычайно важна этапность и при-менение современных высокоинформативных методик [4,5,20]. В ранней доклинической диагностике ГПЭ для опре-деления показаний к гистологическому исследованию не утратила своей актуальности ультразвуковая диагностика, преимущественно трансвагинальная эхография с проведе-нием допплерографических и допплерометрических ис-следований эндометрия, количественной оценки его кро-воснабжения, что требует отдельного изложения в наших дальнейших публикациях.…”
Section: Introductionunclassified