Hyperplastic processes of endometrium: what's new?

Татарчук, Т. Ф; Калугина, Л. В.; Тутченко, Т. Н.

doi:10.18370/2309-4117.2015.25.7-13

Cited by 10 publications

(3 citation statements)

References 13 publications

(22 reference statements)

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“…Гіперпроліферативні процеси ендометрія (ГПЕ)патологія жіночої репродуктивної системи, що зустрічається у пацієнток різних вікових груп [2,3,5]. В останні десятиліття у світі спостерігається тенденція до збільшення кількості хворих та частоти малігнізації ГПЕ, що пов'язують із збільшенням числа жінок, які страждають на нейроендокринну патологію, з ростом числа хронічної соматичної патології, зниженням імунітету та несприятливими умовами навколишнього середовища [2,3,6].…”

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“…Не слабшає інтерес до вивчення проблеми ГПЕ у зв'язку з неуклінним ростом кількості хворих на гіперплазію та рак ендометрія, тенденцією до онкотрансформації та схильністю до рецидивування [4,5,7,8]. У 70% випадків рак ендометрія розвивається на тлі ГПЕ, і в 30-79% протягом 1-3 років атипова гіперплазія ендометрія перероджується в рак [1,9].…”

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Assessment of risk factors for the development of simple and complex non-atypical endometrial hyperplasia

Bykova¹

2020

Rep. of Vinnytsia Nation. Med. Univ.

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Annotation. Goal – to identify and assess the most significant risk factors for the development of simple non-atypical endometrial hyperplasia (SNAEH) and complex non-atypical endometrial hyperplasia (CNAEH) in women. Retrospective analysis of anamnestic data of 58 case histories of patients with SNAEH, 35 case histories of patients with CNAEH and data of 30 women of the control group, which allowed to identify risk factors for hyperproliferative processes of the endometrium (HPE) for research, the statistical significance of which was further assessed by calculating odds ratio (OR). The main feature associated with the risk of SNAEH is heredity – OR = 49.73 (95% CI 2.90–852.32). Significantly increases the risk of developing SNAEH in the presence of thyroid gland lesion (TGL) – OR = 34.97 (95% CI 2.03–601.20). The third in the hierarchical sequence is the polycystic ovary syndrome factor; OR = 25.72 (95% CI 1.488–444.59). Heredity occupies the top of the hierarchical structure in the group of patients with CNAEH. OR is 80.67 (95% CI 4.56–1424.76). A high probability of developing CNAEH is also observed for women over the age of 50 (OR = 32.44 (95% CI 1.82–576.56). In third place – the presence of TGL, which significantly increases the risk of developing CNAEH; OR = 28.63 (95% CI 1.60–510.56) Identification of statistically significant risk factors for the development of HPE will help to identify risk groups among the population, to carry out preventive measures among them (lifestyle adjustments, treatment of concomitant diseases) and decrease the incidence of the HPE.

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Assessment of risk factors for the development of simple and complex non-atypical endometrial hyperplasia

Bykova¹

2020

Rep. of Vinnytsia Nation. Med. Univ.

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“…ендометрію [5,6] та новоутворень порожнини матки [7]. Тому одною з найпопулярніших маніпуляцій є вишкрібання порожнини матки (ВПМ), яке має важливе діагностичне та лікувальне значення.…”

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The influence of various anesthetic thechniques on life quality of patients during the postoperative period after curettage of the uterine cavity

Georgiyants¹,

Dotsevych²,

Vуsotska³

et al. 2019

ScienceRise: Medical Science

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Optimization of treatment of endometrial hyperplastic processes in the late reproductive period by hysteroscopic сold loop technique

Корнієнко

2017

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The aim of the study was to evaluate the effectiveness of various methods of hyperplastic endometrium removing in late reproductive age women.Materials and methods. In the prospective cohort study 321 women 35–44 year aged with hyperplastic endometrium processes were selected by the continuous sample method. Depending on the method of treatment of this pathology, the patients were divided into two groups: the Ith group included 143 women whom, after hysteroscopic confirmation of the diagnosis, the hyperplastic endometrium was removed using the “cold loop” technique with the further complex scheme of treatment which included therapy by synthetic gestagens, sedative therapy and use of drugs of melatonin (in the presence of disorders of a dream and hypomelatoninemia). The II group included 178 women, whom after hysteroscopic confirmation of the diagnosis, curettage of a cavity of the uterus was performed, the subsequent hormonal therapy by synthetic gestagena was used according to the Clinical protocol “Endometrial Hyperplasia” (the order of the MOH of Ukraine No. 676 from 31.12.2004). The women of both groups did not differ significantly by age, menstrual cycle peculiarities, gynecological, reproductive, somatic anamnesis and complaints.Results and conclusions. Analisis of the long-term results of endometrial pathology treatment showed that among I-th group women recurrence of hyperplastic endometrium processes was observed several times less often (p <0.05). The author came to the conclusion that the removal of hyperplastic endometrium by the “cold loop” technique allows to significantly reduce the hyperplastic endometrium processes recurrence and newly detected intrauterine pathology level in comparison with endometrial curretage.

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Hyperplastic processes of endometrium: what's new?

Cited by 10 publications

References 13 publications

Assessment of risk factors for the development of simple and complex non-atypical endometrial hyperplasia

Assessment of risk factors for the development of simple and complex non-atypical endometrial hyperplasia

The influence of various anesthetic thechniques on life quality of patients during the postoperative period after curettage of the uterine cavity

Optimization of treatment of endometrial hyperplastic processes in the late reproductive period by hysteroscopic сold loop technique

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