Intra-erythrocyte chromium as an indicator of exposure to hexavalent chromium: An in vivo evaluation in intravenous administered rat

Abstract

Intra-erythrocyte chromium as an indicator of exposure to hexavalent chromium: an in vivo evaluation in intravenous administered rat.

Carcinogenic Risk of Pb, Cd, Ni, and Cr and Critical Ecological Risk of Cd and Cu in Soil and Groundwater around the Municipal Solid Waste Open Dump in Central Thailand

“…Hexavalent chromium (Cr +6 ) compounds are classified as carcinogenic to humans in the respiratory tract, giving rise to cancer of the lungs, nose, and nasal sinuses. It is mutagenic when inhaled and also potentially when ingested orally in large quantities [104,105]. In particular, in certain occupational environments, workers may suffer from inhalation exposure by Cr +6 dust, mists, and fumes [106].…”

The Effect of Global DNA Methylation on PDCD5 Expression in the PBMC of Occupational Chromate Exposed Workers

“…As a result, Cr in red blood cells can reflect relatively long-term Cr VI exposure levels. 30,32,46 Meanwhile, the urine Cr also can be used as a reliable indicator to assess the extent of relatively shorter-term Cr VI biological exposure. 12,33 Therefore, it is necessary to integrate both RBC Cr and urine Cr to comprehensively evaluate the effects of Cr VI exposure on DNA damage, methylation and cell apoptosis in the occupational chromate exposure population.…”

“…The life span of erythrocytes red blood cells was about 120 days. As a result, Cr in red blood cells can reflect relatively long-term Cr VI exposure levels 30,32,46 . Meanwhile, the urine Cr also can be used as a reliable indicator to assess the extent of relatively shorter-term Cr VI biological exposure 12,33 …”

“…The Cr in urine has been proposed as a biomarker of shorter-term exposure, while the Cr in RBC has been recognized as an indicator of longer-term Cr exposure 12,30–33 . The subgroup analysis refers to the description previously report 34 .…”

“…The Cr in urine has been proposed as a biomarker of shorterterm exposure, while the Cr in RBC has been recognized as an indicator of longer-term Cr exposure. 12,[30][31][32][33] The subgroup analysis refers to the description previously report. 34 Briefly, the Cr VI exposed subjects were divided into four exposure patterns according to both the medium of urine Cr and RBC Cr concentrations.…”