Intra-abdominal Complications of Sarcoidosis

MacArthur, Kristin L.; Forouhar, Faripour; Wu, George Y.

doi:10.1016/s0929-6646(10)60082-4

Cited by 32 publications

(37 citation statements)

References 50 publications

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“…8). Peritoneal biopsy is required to rule out carcinomatosis, tuberculosis, and fungal infections (4,31). Symptoms usually regress without any treatment or with short-term treatment of corticosteroids (39).…”

Section: Peritoneum and Lymph Nodesmentioning

confidence: 99%

“…The etiology of the disease is still not exactly clarified. The lungs and the lymphoid system are the most commonly involved sites with a frequency of 90% and 30%, respectively (4). Extrapulmonary involvement of sarcoidosis is reported in 30% of patients and the abdomen is the most common extrathoracic site with a frequency of 50%-70%.…”

mentioning

confidence: 99%

“…Abdominal sarcoidosis can occur in the absence of lymphatic or pulmonary disease (4). Although usually asymptomatic, the presence of symptomatic abdominal involvement may affect the prognosis and treatment options.…”

mentioning

confidence: 99%

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Abdominal sarcoidosis: cross-sectional imaging findings

Gezer¹,

Başara²,

Altay³

et al. 2015

Diagn Interv Radiol

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Sarcoidosis is a multisystem inflammatory disease of unknown etiology. The lungs and the lymphoid system are the most commonly involved organs. Extrapulmonary involvement is reported in 30% of patients, and the abdomen is the most common extrapulmonary site with a frequency of 50%-70%. Although intra-abdominal sarcoidosis is usually asymptomatic, its presence may affect the prognosis and treatment options. The lesions are less characteristic and may mimick neoplastic or infectious diseases such as lymphoma, diffuse metastasis, and granulomatous inflammation. The liver and spleen are the most common abdominal sites of involvement. Sarcoidosis of the gastrointestinal system, pancreas, and kidneys are extremely rare. Adenopathy which is most commonly found in the porta hepatis, exudative ascites, and multiple granulomatous nodules studding the peritoneum are the reported manifestations of abdominal sarcoidosis. Since abdominal sarcoidosis is less common and long-standing, unrecognized disease can result in significant morbidity and mortality. Imaging contributes to diagnosis and management of intra-abdominal sarcoidosis. In this report we reviewed the cross-sectional imaging findings of hepatobiliary, gastrointestinal, and genitourinary sarcoidosis.

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Section: Peritoneum and Lymph Nodesmentioning

confidence: 99%

mentioning

confidence: 99%

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Abdominal sarcoidosis: cross-sectional imaging findings

Gezer¹,

Başara²,

Altay³

et al. 2015

Diagn Interv Radiol

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“…The lungs and lymph nodes are the most frequently involved organs with a frequency of 90% and 30%, respectively [2]. Less frequently, the skin, liver, and spleen may be involved.…”

Section: Discussionmentioning

confidence: 99%

The Diagnosis and Response to Treatment of an Extrapulmonary Sarcoidosis on F18-FDG PET/CT: A Case Report

Uslu¹,

Yakar²,

Kanbay³

et al. 2017

Ann Clin Anal Med

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“…It is characterized by noncaseating granulomas in the absence of other autoimmune processes, infectious diseases, or foreign agents [1]. It primarily affects the lungs and lymphatic systems.…”

Section: Introductionmentioning

confidence: 99%

Unusual Presentation of a Colonic Sarcoidosis

Daldoul¹,

Triki²,

Jeri

et al. 2012

Case Reports in Medicine

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Sarcoidosis is a multisystemic disorder of unknown cause that affects almost every tissue in the body. Colon is an extremely rare location of this disease. Clinical presentation, endoscopic appearances, and radiologic findings are not specific and may mimic much other affection. We report the case of a 64-year-old woman with inactive pulmonary sarcoidosis who presented alternating constipation and diarrhea. Colonoscopy revealed a stenotic tumor in the ascending colon. Histology failed to determine the nature of the lesion. Radiologic findings are those of a long stenotic tumor of the ascending colon associated with a multiple satellite lymphadenopathy. Endoscopic and radiologic descriptions are highly suggestive of a malignancy. The patient underwent a laparotomy, and a right hemicolectomy was performed. Examination of the resected specimen showed follicular structure with central epitheloid and giant cells and surrounding fibroblasts. These findings made the diagnosis of colonic sarcoidosis. The nonspecificity of the endoscopic and radiological signs of gastrointestinal sarcoidosis and the extreme rarity of colonic location make the preoperative diagnosis unlikely. The diagnosis will be then made only on histological examination of surgical specimens. We describe, through this observation, the results of paraclinical investigations that can suggest diagnosis and perhaps avoid surgery.

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Intra-abdominal Complications of Sarcoidosis

Cited by 32 publications

References 50 publications

Abdominal sarcoidosis: cross-sectional imaging findings

Abdominal sarcoidosis: cross-sectional imaging findings

The Diagnosis and Response to Treatment of an Extrapulmonary Sarcoidosis on F18-FDG PET/CT: A Case Report

Unusual Presentation of a Colonic Sarcoidosis

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