Abdominal sarcoidosis: cross-sectional imaging findings

Gezer, Naciye Sinem; Başara, Işıl; Altay, Canan; Harman, Mustafa; Rocher, Laurence; Karabulut, Nevzat; Seçil, Mustafa

doi:10.5152/dir.2014.14210

Cited by 73 publications

(54 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The lymph nodes are typically smaller than 2 cm in diameter and more discrete rather than confluent, the involvement of the retrocrural area is less common. The characteristics of this lymph nodes on CT are: soft tissue attenuation, mildly enhanced with gadolinium in T1 images and homogeneously hyperintense appearance or central hypointensity surrounded by peripheral high signal intensity on T2 images 7 .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Exclusive abdominal lymphadenopathy as a rare presentation of sarcoidosis

Santos¹,

Carvalho²,

Santos³

et al. 2018

Rev. Med. (São Paulo)

View full text Add to dashboard Cite

Sarcoidosis is a systemic granulomatous disease. The disease’s immunopathogenic mechanism is the activation of a cell mediated immune response. Lung is the most affected organ, but up to 30% of patients can have extrapulmonary manifestations. Case report: A 21-year-old male presented with a history of nausea, vomiting after meals, epigastric and periumbilical pain for approximately 6 months. Hyporexia and loss of 35 kilograms in 7 months were present, in addition to intermittent low nocturnal fever. His computed tomography (CT) scan (Figure 1) of the abdomen showed the presence of multiple, enlarged mesenteric lymph nodes with homogenous shape, measuring up to 2.0 cm in diameter, extending from the upper abdomen to the pelvis. Histopathologic findings of this lymph nodes showed a sarcoid appearance (Figure 2). Lymphoma, tuberculosis and other infections were excluded through immunohistochemical analysis. Treatment with prednisone was started initially at a dose of 40mg and after 5 weeks the patient were asymptomatic. One year and three months after the onset of treatment, corticosteroid dose reduction was attempted 3 times, with all of them leading to disease relapses. Treatment was optimized with 60mg of prednisone (for 2 weeks) plus 100mg of azathioprine daily. Discussion: The prevalence of gastrointestinal system involvement with clinical manifestations is 0,1 to 0,9%. However, the incidence of subclinical involvement can be higher. Enlarged lymph nodes is present in approximately 30% of cases. Treatment is indicated in sarcoidosis for patients with damage organ function or symptomatic disease and the first-line therapy is corticosteroid.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Sarcoidosis is a systemic disease of unknown etiology, characterized by the formation of noncaseating granulomas. Although pulmonary involvement is the most common, 30% of patients present with extrapulmonary sarcoidosis, being the abdomen the most common extrathoracic site (50-70%) 7 .…”

Section: Discussionmentioning

confidence: 99%

Exclusive abdominal lymphadenopathy as a rare presentation of sarcoidosis

Santos¹,

Carvalho²,

Santos³

et al. 2018

Rev. Med. (São Paulo)

View full text Add to dashboard Cite

show abstract

“…Abdominal manifestations of sarcoidosis are common if paucy-or asymptomatic forms of the disease are considered, with a reported frequency of 50-70% [1]. Virtually every organ can be involved by sarcoid lesions, but liver and spleen are the sites most often affected.…”

Section: Editorialmentioning

confidence: 99%

Multiple Facets of Abdominal Sarcoidosis

Tana¹,

Tana²,

Carlo³

et al. 2016

GHOA

View full text Add to dashboard Cite

“…It is usually characterized by hilar lymphadenopathy, pulmonary infiltration, skin, and eye lesions and also noncaseating granulomatous inflammation in the affected organs (1,2). It most commonly involves the lungs.…”

Section: Anahtar Sözcükler: Sarkoidoz Dalak Intra-abdominal Dalakmentioning

confidence: 99%

Nodular Splenic Sarcoidosis: A Rare Case Report

Çalık¹,

Yesildag²,

Calik³

et al. 2017

Respir Case Rep

View full text Add to dashboard Cite

Sarcoidosis is an idiopathic, multi-systemic, granulomatous disease. It most commonly involves the lungs. Herein, we present a rare and usually asymptomatic case with splenic sarcoidosis without liver involvement. A 31-year-old male patient was admitted to our clinic with cough, sputum, and shortness of breath. He reported no common systemic complaints of sarcoidosis. Thoracic and abdominal computed tomography showed multiple hypodense mediastinal lymph nodes with splenic involvement. No other intra-abdominal pathology or peripheral lymphadenopathy was detected. Mediastinoscopy was performed. Diagnosis was made histopathologically. Following the treatment, his complaints regressed. Nodular splenic involvements are uncommon. Although there have been reported thirty-nine cases of sarcoidosis with multiple nodular hepatic and splenic lesions, only three isolated splenic cases have been reported in the literature to date. Despite its rarity, extra-pulmonary sarcoidosis may cause significant morbidity and mortality. Therefore, we discuss this case to draw attention to splenic sarcoidosis without liver involvement and its manifestations, diagnosis, and clinical course.

show abstract

Abdominal sarcoidosis: cross-sectional imaging findings

Cited by 73 publications

References 54 publications

Exclusive abdominal lymphadenopathy as a rare presentation of sarcoidosis

Exclusive abdominal lymphadenopathy as a rare presentation of sarcoidosis

Multiple Facets of Abdominal Sarcoidosis

Nodular Splenic Sarcoidosis: A Rare Case Report

Contact Info

Product

Resources

About