Intoxication par brunneoincarnata : à propos de deux cas

First Report of a Neotropical Agaric (Lepiota spiculata, Agaricales, Basidiomycota) Containing Lethal α-Amanitin at Toxicologically Relevant Levels

“…brunneoincarnata and L . subincarnata ( Roux et al, 2008 ; Khelil et al, 2010 ; Mottram et al, 2010 ; Diaz, 2018 ; Sun et al, 2019 ). Lethal Lepiota species usually produce more than one type of amatoxin, for example, L. brunneoincarnata contains both α- and β-amanitin ( Yilmaz et al, 2015 ), whereas α- and γ-amanitin are present in L .…”

Phalloides Syndrome Poisoning After Ingestion of Lepiota Mushrooms

“…However, some deaths, including in pediatric cases, after consumption of Lepiota species have been reported in the medical literature. 3,4 Moreover, in a mushroom-poisoned patient, other factors are important such as personal tolerance, body weight, and general health. However, the intensive reaction of the young boy could be explained by the relatively large amount of mushroom eaten and a small body weight (30 kg).…”

“…No antidote with proven efficacy for treatment of phalloides poisoning is available, but 3 major products have been described as useful at the choleriform stage. 2 ,3,5 Penicillin G may have a preventive effect by inhibiting α-amanitin uptake by hepatocytes. Silibinin has been recommended as a hepatoprotector and a glutathione precursor.…”

“…Liver transplantation or albumin liver dialysis, eg, molecular adsorbents recirculation system (MARS) therapy, may be proposed as a last resort. 3…”