Intoxicación por paraquat: presentación de dos casos y revisión de la literatura

Gonzalez, António; González, Juan F.; Heras, Manuel; Fernández, Carmen Mora; Serrano, Mario; Pérez, J García

doi:10.4321/s0212-71992001000400009

Cited by 4 publications

(4 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Os primeiros casos fatais foram acidentais e ocorreram em 1964, mas só foram relatados em 1966 (10) . Desde então, têm sido reportadas várias mortes resultantes de intoxicações ocupacionais, acidentais ou suicidas (23,43,58,62) . É um sólido incolor, cristalino e higroscópico cuja fórmula molecular é C 12 H 14 N 2 com peso molecular de 186,25.…”

Section: Aspectos Gerais E Históricos Do Herbicidaunclassified

Aspectos gerais e diagnóstico clinicolaboratorial da intoxicação por paraquat

Schmitt¹,

Paniz²,

Grotto³

et al. 2006

J. Bras. Patol. Med. Lab.

View full text Add to dashboard Cite

Section: Aspectos Gerais E Históricos Do Herbicidaunclassified

Aspectos gerais e diagnóstico clinicolaboratorial da intoxicação por paraquat

Schmitt¹,

Paniz²,

Grotto³

et al. 2006

J. Bras. Patol. Med. Lab.

View full text Add to dashboard Cite

“…Sem dúvida, o maior interesse no tratamento das intoxicações por paraquat tem se concentrado em medidas que impeçam ou minimizem as lesões celulares, principalmente aquelas provocadas por ele nos diversos órgãos atingidos, como nos pulmões (RIVERO GONZÁLES et al, 2001;SERRA et al, 2003). A ação tóxica do herbicida deve-se à ocorrência de uma reação Ciência Rural, v.37, n.5, set-out, 2007. cíclica de oxirredução com formação de radicais livres, especialmente nos pneumócitos do tipo I e II.…”

Section: Tratamentounclassified

Os riscos e danos nas intoxicações por paraquat em animais domésticos

et al. 2007

View full text Add to dashboard Cite

show abstract

“…Paraquat suicides have been reported as “alarming” in some rural contexts, overcoming homicidal and accidental exposures, where they represent the second cause of poisoning 2,16 : the subjects involved voluntarily ingest large quantities of the herbicide that rapidly exerts a high intrinsic local irritant toxicity, with systemic symptoms that appear later. Literature also describes some rare cases of parenteral injections of PQ for suicide purposes 5,17,18 …”

mentioning

confidence: 99%

“…Significant absorptions occur through contact with large abraded or deepithelized skin surfaces and in case of prolonged adhesion of PQ-impregnated clothing, perhaps as a result of accidental leakage from containers carried on the shoulders of agricultural operators. 14,15 Paraquat suicides have been reported as "alarming" in some rural contexts, overcoming homicidal and accidental exposures, where they represent the second cause of poisoning 2,16 : the subjects involved voluntarily ingest large quantities of the herbicide that rapidly exerts a high intrinsic local irritant toxicity, with systemic symptoms that appear later. Literature also describes some rare cases of parenteral injections of PQ for suicide purposes.…”

mentioning

confidence: 99%

A Forensic Case of Suicide Ingestion of Paraquat Herbicide

Tambuzzi,

Vacchiano,

Gentile

et al. 2023

Am J Forensic Med Pathol

View full text Add to dashboard Cite

Paraquat (PQ) is one of the most widely used herbicides in the world, and poisoning is generally associated with accidental, suicidal, or homicidal events. Therefore, in the forensic context, PQ could be in various ways involved as a possible cause of death of a subject. However, even though its systemic toxicity is known, the biological effects exerted on individual viscera have been explored only to some extent, especially in case of victim's survival. Therefore, a case concerning a suicidal ingestion of PQ with survival of 3 days was deemed of interest. Clinical toxicological analyses confirmed acute PQ intoxication, and after the death of the victim, an autopsy was performed showing local and systemic signs of ingestion of a caustic substance. Histologic examination revealed marked cellular damage to the major viscera, particularly the gastroesophageal tract, liver, kidneys, and lungs, with initial alveolar fibrosis noted despite the patient's short survival. This finding represents a new element in the context of PQ lung injury, as it has not been previously documented in the literature. Thus, histological findings in lethal intoxications after survival can reveal specific peculiarities still unknown and, therefore, assume transversal relevance not only at forensic but also clinical level.

show abstract

Intoxicación por paraquat: presentación de dos casos y revisión de la literatura

Cited by 4 publications

References 12 publications

Aspectos gerais e diagnóstico clinicolaboratorial da intoxicação por paraquat

Aspectos gerais e diagnóstico clinicolaboratorial da intoxicação por paraquat

Os riscos e danos nas intoxicações por paraquat em animais domésticos

A Forensic Case of Suicide Ingestion of Paraquat Herbicide

Contact Info

Product

Resources

About