Intestinal fistula output in regular, elemental, and intravenous alimentation

Wolfe, Bruce M.; Keltner, Raymond M.; Willman, Vallee L.

doi:10.1016/0002-9610(72)90144-4

Cited by 52 publications

(13 citation statements)

References 6 publications

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“…The physiological alterations in ileostomy fluid with elemental diet ingestion which have been demonstrated in the present study therefore may be presumed to be similar to those occurring in the surgical patient with a low small bowel fistula. These data show that a more fluid, and presumably less corrosive, drainage is produced from a low small bowel fistula when an elemental diet is administered, although these favourable changes do not appear in every patient and they may be less than some previous reports have suggested (Wolfe et al, 1972). This favourable alteration in the nature of the discharge together with the proved ability of these diets to maintain body weight and positive nitrogen balance (Bounos et al, 1967;Bury et al, 1971 ;Voitk et al, 1973) helps to explain the success achieved by these diets in closing gastro-intestinal fistulas.…”

Section: Discussioncontrasting

confidence: 48%

Decreased trypsin and bile acids in ileal fistula drainage during the administration of a chemically defined liquid elemental diet

Hill

Mair

Edwards

et al. 1976

British Journal of Surgery

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Ten patients with a well-established ileostomy were studied in a metabolic ward and alterations in ileostomy contents of trypsin and bile acids were measured during the ingestion of an elemental diet. After a 4-day control study the patients were given an elemental diet as the sole nutritional source for a 10-day period. For the last 3 days of the study an additional 2 litres of water were consumed with the elemental diet. The mean daily faecal output for the group during the control period was 578 +/- 300 ml, and during administration of the elemental diet the fistula output fell to 418 +/- 190 ml (P less than 0-02) and there was a fall in the concentration of sodium in the ileal fluid (104-7 +/- 22 mEq/l to 80-2 +/- 25 mEq/l, P less than 0-01). For the group as a whole there was a fall in the concentration of trypsin (0-671 +/- 0-53 i.u./ml to 0-554 +/- 0-56 i.u./ml, P less than 0-025) and bile acids (0-911 +/- 0-56 mmol/ml to 0-662 +/- 0-53 mmol/ml, P less than 0-005) in the ileal excreta. Althoug the concentration of amylase in the ileal fluid rose, the total output was not altered. Oral administration of an additional 2 litres of water did not later the concentration of trypsin or bile acids in the ileal fluid. It is concluded that elemental diet ingestion produces changes in ileal fistula output which are of benefit to the patient with an enterocutaneous fistula. Output from the fistula of fluid and electrolyte is less and the corrosive nature of the discharge is reduced.

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Section: Discussioncontrasting

confidence: 48%

Decreased trypsin and bile acids in ileal fistula drainage during the administration of a chemically defined liquid elemental diet

Hill

Mair

Edwards

et al. 1976

British Journal of Surgery

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“…Horses [1,12,18,30,31,44,49], cows [42], dogs [10,11,17,28,29,35,46,51], turkeys [39] and above all rodents have been chosen for study.…”

Section: Discussion Of Methodsmentioning

confidence: 99%

Creation of a caecostoma in mice as a model of an enterocutaneous fistula

Bültmann¹,

Philipp²,

Ladeburg

et al. 1998

Res. Exp. Med.

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In the past, physiological, oncological and pharmaceutical investigations led to the development of different models of enterocutaneous fistulas. For a few years, fistula models were also created to investigate the efficacy of minimal invasive therapies in closing these fistulas. As most experimental surgical procedures are difficult to perform and are often combined with a high mortality or spontaneous closure rate, a new model in mice was developed with the aim of avoiding these disadvantages. Twenty mice, divided into two groups of 10 animals each, had a caecostoma created surgically. The two groups differed regarding the technique of creating the stoma. All animals survived and gained weight during a postoperative period of 4 months. The operation was easy to perform and lasted no longer than about 30 min. Neither a spontaneous closure of the fistula nor any prior death of animals occurred. In conclusion, because of its simplicity and low complication rate, the presented model of an enterocutaneous fistula may offer an interesting alternative to other models for a variety of indications.

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“…Neuere Pr~iparate enthalten auch Oligosaccharide und Oligopeptide. Die Sekretion von Verdauungss~iften ist stark herabgesetzt [4,12,20], und die Resorption erfolgt im obersten D/inndarm [4,17]. Die Sekretion von Verdauungss~iften ist stark herabgesetzt [4,12,20], und die Resorption erfolgt im obersten D/inndarm [4,17].…”

Section: Methodikunclassified

“…Die Sekretion von Verdauungss~iften ist stark herabgesetzt [4,12,20], und die Resorption erfolgt im obersten D/inndarm [4,17]. Bei Dtinndarmfisteln wird unter SD im Vergleich zu konventioneller Schonkost die Fistelsekretion regelm~iBig gesenkt und die Nahrungsabsorption verbessert [4,20]. Somit ergibt sich eine weitgehende Entlastung des Darmtraktes, welche zusammen mit der verbesserten Em/ihrung fiir den g/instigen EinfluB der SD verantwortlich ist.…”

Section: Methodikunclassified

Behandlung von postoperativen Darmfisteln mit schlackenfreier synthetischer Di�t

Göschke

Leutenegger

Mannhardt

et al. 1978

Langenbecks Arch Chiv

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From 1973-1976 sixteen patients with clinically manifest post-operative fistulas (7 small intestinal and 9 colonic) were studied. These patients received an elemental diet (ED) as their only nutritional support for 9-44 days. On ED spontaneous closure was observed in 4 out of 7 small intestinal fistulas and in 7 out of 9 colonic fistulas. Hemoglobin and serum albumin increased significantly on ED and nitrogen balance performed on 7 patients was in equilibrium or positive. Advantages of ED over intravenous nutrition in the treatment of intestinal fistulas are discussed.

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Intestinal fistula output in regular, elemental, and intravenous alimentation

Cited by 52 publications

References 6 publications

Decreased trypsin and bile acids in ileal fistula drainage during the administration of a chemically defined liquid elemental diet

Decreased trypsin and bile acids in ileal fistula drainage during the administration of a chemically defined liquid elemental diet

Creation of a caecostoma in mice as a model of an enterocutaneous fistula

Behandlung von postoperativen Darmfisteln mit schlackenfreier synthetischer Di�t

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