Interventions for promoting physical activity in people with neuromuscular disease

Jones, Katherine; Hawke, Fiona; Newman, Jane; Miller, James; Burns, Joshua; Jakovljevic, Djordje G.; Gorman, Gráinne; Turnbull, Douglass M.; Ramdharry, Gita

doi:10.1002/14651858.cd013544.pub2

Cited by 9 publications

(9 citation statements)

References 108 publications

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“…Exercise based and physical activity is the primary form of rehabilitation in people affected by FSHD. Most physical activity strategies in people affected by neuromuscular conditions, including FSHD, focus on the lower limb and address exercise components related to weightbearing, functional, stretching and sensor-based exercise programmes [8]. It has been identified that existing strategies and methods used to elicit increases in physical activity are not explicit [8].…”

Section: Introductionmentioning

confidence: 99%

“…Most physical activity strategies in people affected by neuromuscular conditions, including FSHD, focus on the lower limb and address exercise components related to weightbearing, functional, stretching and sensor-based exercise programmes [8]. It has been identified that existing strategies and methods used to elicit increases in physical activity are not explicit [8]. Most studies do not meet the minimum requirements recommended for strength training [9][10][11], whilst only one study has met the requirements recommended for physical activity related to cardiovascular respiratory fitness [11].…”

Section: Introductionmentioning

confidence: 99%

“…The overall effectiveness of exercise interventions for increasing physical activity in people with FSHD and neuromuscular disorders is uncertain [8]. It appears that existing exercise interventions may positively influence overall physical fitness, work capacity, quality of life and fatigue resistance, whilst having limited influence on function, strength and pain [8]. However, this needs to be considered alongside the methodological limitations of the studies on which these conclusions are based [8,11].…”

Section: Introductionmentioning

confidence: 99%

“…It appears that existing exercise interventions may positively influence overall physical fitness, work capacity, quality of life and fatigue resistance, whilst having limited influence on function, strength and pain [8]. However, this needs to be considered alongside the methodological limitations of the studies on which these conclusions are based [8,11]. Some studies have shown that exercise with moderate weights or resistance is not detrimental to people with FSHD [12,13] and that consistent aerobic training in people with FSHD may improve improves cardiovascular fitness and strength concomitantly [14].…”

Section: Introductionmentioning

confidence: 99%

“…There is therefore limited evidence available to inform clinical practice and support strategies for improving physical activity and exercise for people affected by FSHD [8]. This includes identification of measures e.g.…”

Section: Introductionmentioning

confidence: 99%

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A pilot study of a single intermittent arm cycling exercise programme on people affected by Facioscapulohumeral dystrophy (FSHD)

et al. 2022

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For patients affected by Facioscapulohumeral dystrophy (FSHD), alternate methods for increasing physical activity engagement that may benefit shoulder function and wider health are needed. Arm cycling has been proposed as a potential method for achieving this although dosage parameters and evidence is limited. The aim of this study was to conduct a pilot study evaluating the effect of a single intermittent arm cycling exercise programme on people affected by FSHD. People with confirmed genetic diagnosis of FSHD between the ages 18–60 years were recruited to attend a single session for the exercise intervention (5 exercise efforts lasting 2 minutes each with 30 seconds of rest between each effort). Prior to exercise, measures of shoulder function (Oxford shoulder score), strength and range of movement were recorded. During the exercise participants were video recorded to quantify range of movement and extract movement profile features. Participants comments were recorded and followed up four days later to check for adverse events. Fifteen participants, (6F:9M) were recruited with median (IQR) Oxford Shoulder Scores of 25 (18 to 39). All participants successfully completed the exercise intervention with only transient symptoms consistent with exercise being reported and achieving a median (IQR) rate of perceived exertion scores of 13 (12 to 13). Movement profile data was available for 12 out of 15 participants and suggests that exercise intensity did not compromise movement. An association between strength and shoulder function (R2 = 0.5147), Rate of perceived exertion (RPE) of the final effort against shoulder function and strength (R2 = 0.2344 and 0.1743 respectively) was identified. Participant comments were positive regarding the exercise intervention. Our study demonstrates that an intermittent arm cycling programme is feasible for people affected by FSHD. Further work is needed to evaluate physiological responses to exercise across variations in programme variables and equipment set up in a larger sample of people affected by FSHD.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

A pilot study of a single intermittent arm cycling exercise programme on people affected by Facioscapulohumeral dystrophy (FSHD)

et al. 2022

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Interventions for promoting physical activity in people with neuromuscular disease

Jones

Hawke

Newman

et al. 2021

Cochrane Database of Systematic Reviews

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Effects of intensive rehabilitation on functioning in patients with mild and moderate Charcot–Marie-Tooth disease: a real-practice retrospective study

Ferraro¹,

Calafiore²,

Curci³

et al. 2023

Neurol Sci

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Charcot–Marie-Tooth (CMT) disease is one of the most common inherited neuropathies and can lead to progressive muscular weakness, pes cavus, loss of deep tendon reflexes, distal sensory loss, and gait impairment. There are still no effective drugs or surgical therapies for CMT, and supportive treatment is limited to rehabilitative therapy and surgical treatment of skeletal deformities. Many rehabilitative therapeutic approaches have been proposed, but timing and cadence of rehabilitative intervention are not clearly defined, and long-term follow-up is lacking in literature. The aim of this real-practice retrospective study was to assess the effectiveness of an intensive neurorehabilitation protocol on muscle strength and functioning in CMT patients. We analyzed data of patients with diagnosis of mild to moderate CMT. The rehabilitation program lasted 2–4 h a day, 5 days a week, for 3 weeks and consisted of manual treatments, strengthening exercises, stretching, core stability, balance and resistance training, aerobic exercises, and tailored self-care training. Data were collected at baseline (T0), after treatment (T1), and at the 12-month mark (T2) in terms of the following outcome measures: muscle strength, pain, fatigue, cramps, balance, walking speed, and ability. We included 37 CMT patients with a median age of 50.72 ± 13.31 years, with different forms: demyelinating (n = 28), axonal (n = 8), and mixed (n = 1). After intensive rehabilitation treatment, all outcomes significantly improved. This improvement was lost at the 1-year mark. Taken together, these findings suggest that an intensive rehabilitation program improves short-term symptoms and functional outcomes in a cohort of inpatients affected by mild to moderate CMT.

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Interventions for promoting physical activity in people with neuromuscular disease

Abstract: Analysis 4.2. Comparison 4: An aerobic exercise programme compared to no aerobic exercise programme in people living with NMD, Outcome 2: Disease-specific quality of life questionnaire

Cited by 9 publications

References 108 publications

A pilot study of a single intermittent arm cycling exercise programme on people affected by Facioscapulohumeral dystrophy (FSHD)

A pilot study of a single intermittent arm cycling exercise programme on people affected by Facioscapulohumeral dystrophy (FSHD)

Interventions for promoting physical activity in people with neuromuscular disease

Effects of intensive rehabilitation on functioning in patients with mild and moderate Charcot–Marie-Tooth disease: a real-practice retrospective study

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