Interventionelle Therapie von primären und sekundären Tumoren der Wirbelsäule

Brado, M.; Hj, Hansmann; Gm, Richter; Gw, Kauffmann

doi:10.1007/s001320050230

Cited by 8 publications

(3 citation statements)

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“…The latter entail radiation therapy, surgical stabilization or vertebrectomy, and palliative therapy [8]. Since its introduction during the 1990s, percutaneous vertebroplasty (PV) has been progressively developed and adopted to treat spinal metastases.…”

Section: Introductionmentioning

confidence: 99%

Percutaneous Selective Vertebroplasty: State of the Art Management in Well-Confined Metastatic Vertebral Lesions

Elnoamany

2016

Asian Spine J

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Study DesignProspective cohort study.PurposeTo evaluate the clinical and radiological results of percutaneous selective vertebroplasty (PSV) as first-line treatment options in the setting of well-confined spinal metastases.Overview of LiteratureRecent technological advances combined with innovative interventional techniques enable an alternative less invasive treatment option for many patients with malignant vertebral body infiltration. Percutaneous vertebral augmentation procedures offer less invasive but effective pain relief to many patients with symptomatic spinal metastatic disease.MethodsEleven patients with 21 well-confined metastatic vertebral lesions that had been treated with PSV were included. Pain was evaluated one week, one month, 3 months and 6 months post-procedure using a 10-point visual analogue scale (VAS). A statistical analysis including repeated measures analysis of variance test was used to collectively indicate the presence of any significant differences between different time sequences. Medication usage and range of mobility were also evaluated.ResultsThe 11 patients had an average age of 42 years and 54.5% were male. Highly significant improvements in VAS scores at rest and with activity (p<0.001) were evident. There was a significant decrease in rate of medication consumption post-procedure (p<0.05).ConclusionsPSV can be used successfully as the first-line treatment for well-confined metastatic vertebral lesions. It is also an effective method to decrease pain, increase mobility, and decrease narcotic administration in such patients.

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Section: Introductionmentioning

confidence: 99%

Percutaneous Selective Vertebroplasty: State of the Art Management in Well-Confined Metastatic Vertebral Lesions

Elnoamany

2016

Asian Spine J

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“…neurologischer Defizite [1]. Die Tumorchirurgie an der Wirbelsäu-le ist in über 98% der Fälle eine palliative Therapie und dient nicht der Lebensverlängerung der Patienten [4,9,14,15,29]. Das primäre Behandlungsziel ist die Verminderung von Schmerzen und/oder neurologischen Ausfallerscheinungen und somit die Erhöhung der Lebensqualität der betroffenen Patienten.…”

Section: Operationsindikation Und Therapiezielunclassified

Komplikationen bei operativer Dekompression an der tumorinfiltrierten Wirbelsäule

Hessler

Raimund

Regelsberger

et al. 2007

Chirurg

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“…Ziel der präoperativen Embolisation ist der komplette Verschluß des Kapillarbettes, was nur durch flüssige Embolisate wie Ethanol oder Ethibloc® erreicht werden kann [19,20,21]. Die Indikation beschränkt sich daher auf die symptomatische Therapie bei Eintreten einer Hämaturie oder therapieresistenten Schmerzen oder auch die Embolisation von symptomatischen Skelettmetastasen [22]. Ethibloc® ist eine relativ visköse, gesättigte alkoholische Lösung des wasserunlöslichen Getreideproteines Zein, das durch Beifügung von jodiertem nalen OP-Risiko können von einer Embolisation etwa in gleichem Maße profitieren wie von einer chirurgischen Resektion [19][20][21].…”

Section: Tumorembolisationunclassified

Angiographie und interventionelle Radiologie der Nieren

et al. 1999

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For imaging of renal pathology a broad spectrum of radiologic diagnostic procedures are available which are, sometimes and particularly more recently, competing among each other in their diagnostic yield and relevance. For tumorous lesions ultrasound, computed tomography and magnetic resonance imaging are performed predominantly. Angiography is no longer required with the exception of highly selected cases and in some specific preoperative workup requirements. Until recently, catheter based digital subtraction angiography has been considered as gold standard. However, non-invasive techniques such as CT-angiography and MR-angiography are evolving parallel to their quantum leap of resolutions and readiness to use. Nevertheless, well accepted criteria for quality assessement of these new modalities are still lacking. More comparison studies are urgently warranted. Despite the availability of ultrashort pulse sequences applying the T1 relaxation reduction effect of gadolinium enhanced MR techniques overestimation of renal artery stenosis still poses a substantial problem. Renal intervention implies a variety of procedures such as plain angioplasty, stent placement, embolization of traumatic and both benign and malignant tumors. These methods have emerged over the last two decades from a more experimental nature to a fully accepted treatment option. When renal artery angioplasty is embedded in an aggressive approach including stenting as an adjunct for more complex cases, renal ostial lesions and a well organized follow-up regimen its therapeutic potential for treatment of renal insufficiency, malignant hypertension, for organ preservation bears a very high potential. Provided adequat periinterventional drug regimen restenosis rates may be as low as 10%. In highly selected cases capillary embolization might be used as an alternative to nephrectomy with a similar clinical outcome. Particularly the development of superselective small caliber embolization catheters parallel to further refinement of embolization material has aided to use superselective occlusion techniques in benign vascular lesions and renal trauma.

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Interventionelle Therapie von primären und sekundären Tumoren der Wirbelsäule

Cited by 8 publications

References 0 publications

Percutaneous Selective Vertebroplasty: State of the Art Management in Well-Confined Metastatic Vertebral Lesions

Percutaneous Selective Vertebroplasty: State of the Art Management in Well-Confined Metastatic Vertebral Lesions

Komplikationen bei operativer Dekompression an der tumorinfiltrierten Wirbelsäule

Angiographie und interventionelle Radiologie der Nieren

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