“…Recently, a number of in vivo studies using animal models were undertaken where MNPs were injected into a tumor followed by AMF exposure and resulting changes in the tissue and organs were investigated. These include C3H mouse mammary carcinoma [63] , mouse EL4 T-lymphoma [11] , MX11 mouse sarcoma [64] , human prostate cancerous and bone marrow cells in transgenic mice [46] , EL4 mouse T-lymphoma [65] , T-9 rat glioma cells [66] , B16 mouse melanoma [67] , MM46 mammary and skin carcinoma [68] , murine B16-F10 mouse melanoma [69] , cat mammary tumor gland [70] , Os515 hamster osteosarcoma [71] , VX-7 squamous cell carcinoma in rabbit tongue [72] , DMBA induced rat mammary carcinoma [73] , and human glioma cells. [74] Most of the studies though provided positive evidence for decrease in tumor size due to hyperthermia, there is a clear lack of complete information on host and material response.…”