Interstitial cystitis/painful bladder syndrome: symptom recognition is key to early identification, treatment.

Rosenberg, Matt T.; Newman, Diane K.; Page, S

doi:10.3949/ccjm.74.suppl_3.s54

Cited by 21 publications

(17 citation statements)

References 34 publications

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“…Symptoms of PBS/IC typically worsen during the premenstrual week in contrast with endometriosis (36). In addition, because PBS/IC occurs in flares, it is often misdiagnosed as recurrent urinary tract infection (UTI) or prostatitis, with the resolution incorrectly attributed to antibiotic therapy and not to the disease's natural pattern (37). There are no specific physical findings in PBS/IC patients.…”

Section: History and Physical Examinationmentioning

confidence: 99%

Interstitial Cystitis

Moutzouris

Falagas

2009

Clinical Journal of the American Society of Nephrology

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Painful bladder syndrome/interstitial cystitis (PBS/IC) is a chronic disease of unknown etiology characterized by vague bladder pain and nonspecific urinary symptoms, such as urgency and frequency. Although it was initially considered to be a rare condition, its prevalence has significantly increased, possibly because of different definitions used and greater physician awareness. Because of the multiple diagnostic criteria used, there is significant variation in its prevalence. In addition, there is often a delay in the diagnosis of PBS/IC. It affects predominantly women of middle age, and it significantly decreases quality of life. Diagnosis of PBS/IC is mainly a diagnosis of exclusion; there are no characteristic symptoms or pathognomonic findings. Therefore, it is important to rule out diseases that have a similar clinical picture (i.e., urinary infections, bladder carcinoma) but definite therapies and worse prognosis if left untreated. PBS/IC management suffers from lack of evidence; many therapies are empiric or based on small studies and case series. Treatment includes supportive therapies (psychosocial, behavioral, physical), oral treatments, and intravesical treatments, whereas other more invasive treatments such as electric neuromodulation and reconstructive surgery are reserved for refractory cases. Physicians should always keep in mind the diagnosis of PBS/IC in patients presenting with chronic urinary symptoms after excluding other more common diseases.

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Section: History and Physical Examinationmentioning

confidence: 99%

Interstitial Cystitis

Moutzouris

Falagas

2009

Clinical Journal of the American Society of Nephrology

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“…The most common symptoms include urinary frequency, urinary urgency, nocturia and pain [17]. In the early phase, patients present with few, mild and intermittent symptoms, which become worse as time passes [12,17,18] and tend to stabilize after several years [16]. …”

Section: Clinical Presentationmentioning

confidence: 99%

“…Voiding to avoid urine leakage is common in overactive bladder syndrome (OBS), whereas in IC voiding to relieve pain is typical [19]. ESSIC [18] did not include urgency in the description of patients needing further evaluation for IC since it is the main symptom of OBS, which is more common than IC. NIDDK [4] used the absence of nocturia as an exclusion criterion for IC.…”

Section: Clinical Presentationmentioning

confidence: 99%

“…Pain is the most common and bothersome symptom [17] at diagnosis and a prerequisite for diagnosis according to ESSIC [18]. However, in the early phase many patients report pressure sensation or discomfort on the bladder, but not pain [4], whereas over time they report more intense pain.…”

Section: Clinical Presentationmentioning

confidence: 99%

“…Pain typically is temporarily relieved by voiding [19]. Nevertheless, pain is not always present on bladder filling [18]. It is classically localized to the suprapubic area [20] although both location and character of pain are highly variable; pain may often be localized in lower abdomen, urethra, vaginal area, lower back, scrotum and rectum [13].…”

Section: Clinical Presentationmentioning

confidence: 99%

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