Interscalene brachial plexus anaesthesia with 0.5%, 0.75% or 1% ropivacaine: a double-blind comparison with 2% mepivacaine

Casati, Andrea; Fanelli, Guido; Aldegheri, Giorgio; Berti, Marco; Colnaghi, Eleonora; Cedrati, Valeria; Torri, G.

doi:10.1093/bja/83.6.872

Cited by 70 publications

(47 citation statements)

References 13 publications

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“…Duration of analgesia in our study correlated with studies by Conolly C 4 and Laura Bertini et al 20 Casati et al, 21 Vaghadia et al, 19 Chandini M Soni 18 and Tripathi D et al 22 where they found no statistically significant differences between the two drugs.…”

Section: Variablessupporting

confidence: 90%

A Prospective, Randomised, Double-Blind Comparative Clinical Study of 0.5% Bupivacaine and 0.75% Ropivacaine for Sciatic Nerve Block in Patients Undergoing Elective Below Knee Surgeries

Hegde¹,

Manjunath²

2016

jemds

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BACKGROUNDSciatic nerve block is a useful technique for unilateral lower limb surgeries. Bupivacaine is the most commonly used long acting amide local anaesthetic agent for peripheral nerve blockade. Ropivacaine, a newly introduced amide local anaesthetic is similar to Bupivacaine in structure, less potent than bupivacaine and lacks cardiotoxic potential of Bupivacaine. Hence, this study is taken up to compare the block characteristics of equipotent doses of Bupivacaine and Ropivacaine.

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Section: Variablessupporting

confidence: 90%

A Prospective, Randomised, Double-Blind Comparative Clinical Study of 0.5% Bupivacaine and 0.75% Ropivacaine for Sciatic Nerve Block in Patients Undergoing Elective Below Knee Surgeries

Hegde¹,

Manjunath²

2016

jemds

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“…13 Similar observation was made by Casati et al who worked on brachial plexus block performed with Ropivacaine or Mepivacaine in 60 healthy patients undergoing elective upper limb surgery. 14 In the present study, the onset of motor block was earlier in study group of dexamethasone having the mean value of 18.700±2.718min and in comparison, the control group had a mean value of 17.966±2.747min. which is statistically significant (p>0.05).…”

Section: Resultssupporting

confidence: 47%

Comparative study of ropivacaine alone versus ropivacaine with dexamethasone in supraclavicular brachial plexus block

Krishna¹,

Chandra²,

Chaithanya³

2017

Int Surg J

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INTRODUCTIONPain is an unpleasant effect associated with significant psychological and physiological changes during surgery and post-operative period. Regional anaesthetic techniques have specific advantages either for standalone anaesthesia or as analgesic supplements for intraoperative and postoperative care. Brachial plexus block is often used either as an adjuvant to general anesthesia (GA) or as a sole anesthesia modality. Brachial plexus blockade for ambulatory upper-limb surgery can significantly reduce pain and nausea, allowing for faster discharge. Supraclavicular brachial plexus block is preferred for its rapid onset, reliable anesthesia and as a safe technique for any surgery in the upper extremity that does not involve the shoulder. This is mainly because it is a highly effective analgesia ABSTRACT Background: Brachial plexus block is often used either as an adjuvant to general anesthesia (GA) or as a sole anesthesia modality. Supraclavicular brachial plexus block is preferred for its rapid onset, reliable anesthesia and as a safe technique for any surgery in the upper extremity that does not involve the shoulder. We have attempted to undertake this study to compare the haemodynamic, sensory and motor effects of the anaesthetic effect of Ropivacaine alone and Ropivacaine along with Dexamethasone in Supraclavicular Brachial Block in upper limb surgery. Methods: The total duration of surgery was also comparable in both groups. The onset of the sensory and the motor block in bother the groups were similar to each other with no statistical difference, but there was a very high significance in the duration of both sensory and motor block within both the groups. Results: The total duration of surgery was also comparable in both groups. The onset of the sensory and the motor block in bother the groups were similar to each other with no statistical difference, but there was a very high significance in the duration of both sensory and motor block within both the groups. Conclusions: Dexamethasone added to ropivacaine in supraclavicular brachial block for upper limb surgery significantly shortens the onset time and prolongs the duration of sensory and motor blocks without producing sedation in patients.

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“…Similar onset times (1 to 3.2 minutes) were recorded with 0.5% ropivacaine injected supraperiosteally for maxillary anesthesia. 6 Some investigators 5,11,12 have confirmed that increasing the concentration of ropivacaine reduces the onset time of peripheral nerve block, presumably because more local anesthetic molecules are available to penetrate the nerve per unit time. Akerman and associates 1 attributed ropivacaine's tendency toward a more rapid onset of action in comparison with bupivacaine to its weaker binding to extraneural fat and tissues and to its greater availability for transfer to the site of action in the nerve.…”

Section: Discussionmentioning

confidence: 99%

“…3,4 Axillary brachial plexus block with ropivacaine provides adequate anesthesia for hand surgery 3 ; interscalene brachial plexus block with ropivacaine produces rapid onset of anesthesia and prolonged postoperative analgesia nearly twofold longer than with mepivacaine. 5 Limited data are available concerning the use of ropivacaine in dental practice. It has been demonstrated that ropivacaine is equivalent in potency and efficacy to bupivacaine (both with 1 : 200,000 epinephrine) for maxillary anterior filtration.…”

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confidence: 99%

Anesthetic Efficacy of Different Ropivacaine Concentrations for Inferior Alveolar Nerve Block

Elsharrawy

Yagiela

2006

Anesthesia Progress

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This study was conducted on 72 American Society of Anesthesiologists class 1 patients scheduled for extraction of a mandibular third molar after inferior alveolar nerve block. Each patient was randomly administered one of the following ropivacaine concentrations: 0.75%, 0.5%, 0.375%, or 0.25% (18 patients per group). Onset of block (mean Ϯ SD) was rapid for both 0.75% (1.4 Ϯ 0.4 minutes) and 0.5% (1.7 Ϯ 0.5 minutes) ropivacaine but significantly slower for the 0.375% (4.2 Ϯ 2.5 minutes) and 0.25% (10.7 Ϯ 3.0 minutes) concentrations. Tooth extraction was performed successfully with the 0.5% and 0.75% concentrations, and supplemental injections were not required. Second injections, however, were required with 0.375% ropivacaine. Anesthesia was unsuccessful in 13 patients given 0.25% ropivacaine even after 3 injections. The mean durations of soft tissue anesthesia were 3.3 Ϯ 0.3 hours and 3.0 Ϯ 0.3 hours for the 0.75% and 0.5% concentrations, but significantly shorter with more dilute concentrations. The duration of analgesia showed a similar pattern, with the 0.75% and 0.5% concentrations producing prolonged analgesia of 6.0 Ϯ 0.4 hours and 5.6 Ϯ 0.4 hours. These results indicate that 0.5% and 0.75% concentrations were effective for intraoral nerve blockade, with both a rapid onset and prolonged duration of pain control.

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Interscalene brachial plexus anaesthesia with 0.5%, 0.75% or 1% ropivacaine: a double-blind comparison with 2% mepivacaine

Cited by 70 publications

References 13 publications

A Prospective, Randomised, Double-Blind Comparative Clinical Study of 0.5% Bupivacaine and 0.75% Ropivacaine for Sciatic Nerve Block in Patients Undergoing Elective Below Knee Surgeries

A Prospective, Randomised, Double-Blind Comparative Clinical Study of 0.5% Bupivacaine and 0.75% Ropivacaine for Sciatic Nerve Block in Patients Undergoing Elective Below Knee Surgeries

Comparative study of ropivacaine alone versus ropivacaine with dexamethasone in supraclavicular brachial plexus block

Anesthetic Efficacy of Different Ropivacaine Concentrations for Inferior Alveolar Nerve Block

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