Interrelationships between diagnosed asthma, asthma-like symptoms, and abnormal airway behaviour in adolescence: the Odense Schoolchild Study.

Siersted, Hans Christian; Mostgaard, G.; Hyldebrandt, N; Hansen, Henrik Steen; Boldsen, Jesper L.; Oxhøj, H

doi:10.1136/thx.51.5.503

Cited by 58 publications

(44 citation statements)

References 21 publications

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“…We believe that underdiagnosis is the cause of the predominance of current rhinitis, as has been mentioned in the case of asthma. 17,18 We observed a predominance of females among the children with rhinitis, which is in agreement with other publications. 19,20 The seasonal variation of allergic rhinitis with increased prevalence during the winter has also been reported.…”

Section: Resultssupporting

confidence: 81%

Prevalência de rinite alérgica em adolescentes do Distrito Federal: comparação entre as fases I e III do ISAAC

Borges¹,

Burns²,

Felizola³

et al. 2006

J. Pediatr. (Rio J.)

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Objectives: To determine the prevalence of allergic rhinitis in a random group of schoolchildren aged 13 to 14 years in Brasilia, Brazil, to evaluate tendencies over 6 years and to compare prevalence rates among different socioeconomic groups. Methods:Two cross-sectional studies were undertaken 6 years apart, using the ISAAC (phases I and III) written questionnaire. Thirty-nine schools were chosen at random from eight administrative regions in Brasilia, and were classified into three groups according to the socioeconomic conditions of the population.Results: A total of 3,009 questionnaires were collected. Of these 53.5% related to female children and 80% to students from public schools. Prevalence rates for diagnosed rhinitis, recent rhinitis and allergic rhinitis were 20, 29.3 and 12.2%, respectively. Rhinitis was more prevalent in private schools than in public ones (17.8 versus 14.1%) and sufferers were predominantly female. Prevalence rates were also higher among populations with higher socioeconomic status (23.5 versus 12.2%). Comparison with the 1996 data revealed significant increases in the prevalence of diagnosed rhinitis (12.7 versus 20%, p = 0.001). These increases were observed at all socioeconomic levels. Conclusion:A large number of 13 and 14-year-old children resident in the Distrito Federal exhibit symptoms indicative of rhinitis and the majority of them have allergic rhinitis.Over a six-year period the prevalence of allergic rhinitis increased significantly, predominantly affecting females and with greater prevalence among students at private school and from families with higher socioeconomic status.J Pediatr (Rio J). 2006;82(2):137-43: Perennial allergic rhinitis, prevalence, adolescent, analysis socioeconomic.

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Section: Resultssupporting

confidence: 81%

Prevalência de rinite alérgica em adolescentes do Distrito Federal: comparação entre as fases I e III do ISAAC

Borges¹,

Burns²,

Felizola³

et al. 2006

J. Pediatr. (Rio J.)

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“…1,22 By comparing the bronchial provocation tests, methacholine was statistically better than both exercise tests because it detected the largest number of patients with asthma (methacholine versus ergometer: p = 0.006; methacholine versus free running: p = 0.002). We also observed that children with PD 20 greater than 3.74 µmol did not show a decrease in FEV 1 after the exercise greater than 20%.…”

Section: Exercise Versus Methacholinementioning

confidence: 99%

“…The highest value of the three FEV 1 measurements was considered to represent each interval. The intensity of the maximum response was assessed by the largest decrease in FEV 1 after the exercise, expressed as percentage of the baseline FEV 1 . A decrease in FEV 1 of at least 10% after the exercise (decrease in baseline FEV 1 /FEV 1 x 100) was considered as a positive response, since this value represents twice the coefficient of variation for the FEV 1 measurement.…”

Section: Cycle Ergometer Exercisementioning

confidence: 99%

“…Some authors also observed that bronchial provocation challenge by exercise and methacholine or histamine does not always identify the same individuals. 1,8 Different exercise modalities seem to result in different degrees of bronchospasm. Some studies found the following decreasing order in exercise-induced bronchospasm (EIB), when a similar exercise load was used: free running > treadmill running > cycle ergometer > swimming.…”

Section: Introductionmentioning

confidence: 99%

“…There is no gold standard for the diagnosis of asthma 1 , and the disease often is diagnosed by the combination of detailed clinical history, presence of totally or partially reversible bronchial obstruction after the use of a bronchodilator and diurnal variation of airway obstruction. However, the symptoms of asthma are nonspecific and may occur in isolation.…”

Section: Introductionmentioning

confidence: 99%

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Testes de broncoprovocação com metacolina e com exercício em bicicleta e corrida livre em crianças com asma intermitente

Souza¹,

Pereira²

2005

J. Pediatr. (Rio J.)

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Suggested citation: Souza AC, Pereira CA. Bronchial provocation tests using methacholine, cycle ergometer exercise and free running in children with intermittent asthma. J Pediatr (Rio J). 2005;81:65-72. AbstractObjective: To compare airway responsiveness to methacholine, cycle ergometer exercise and free running in children with intermittent asthma.Methods: A randomized study was conducted with 30 children of both genders with intermittent asthma. Each child was submitted to challenge testing on three separate days, in random order: a) Methacholine challenge using a dosimeter; b) Exercise challenge testing free running along a 50-meter-long corridor; c) Dry-air exercise challenge on a cycle ergometer. Target heart rate during exercise was 80 to 90% of the maximum predicted value. Spirometry was performed 3, 6,10,15,20 and 30 minutes after exercise. Exercise-induced bronchospasm was defined as a decrease in FEV 1 of > 10% in comparison to pretest values.Results: Mean age was 11±3 years. FEV 1 and FEV 1 /FVC ratios were normal and similar before all provocation tests. The maximum heart rate was 178±7 bpm during cycling and 181±6 bpm during the free running test (p > 0.05). Significant bronchospasm was observed with methacholine in 23 cases, after free running in 19 and after cycling in 14 children (p < 0.05, methacholine vs exercise tests). Taking all FEV 1 measurements after exercise into account, the free running test resulted in greater exercise-induced bronchospasm in comparison with exercise made on a cycle ergometer (p = 0.003, χ 2 = 8.948). There was a significant, but poor, correlation between the maximum percentage decrease in FEV 1 after free running and cycling (r = 0.46, p < 0.01). Conclusions:Methacholine challenge identifies a greater number of asthmatics in comparison to exercise tests. When bronchial provocation test with methacholine is not available, free running should be the test of choice due to its simplicity and greater ability to induce bronchospasm. J Pediatr (Rio J). 2005;81(1):65-72: Asthma, bronchial provocation tests, methacholine chloride, exercise test, exercise-induced asthma.

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Interrupter technique for evaluation of exercise-induced bronchospasm in children

et al. 1999

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Interrelationships between diagnosed asthma, asthma-like symptoms, and abnormal airway behaviour in adolescence: the Odense Schoolchild Study.

Cited by 58 publications

References 21 publications

Prevalência de rinite alérgica em adolescentes do Distrito Federal: comparação entre as fases I e III do ISAAC

Prevalência de rinite alérgica em adolescentes do Distrito Federal: comparação entre as fases I e III do ISAAC

Testes de broncoprovocação com metacolina e com exercício em bicicleta e corrida livre em crianças com asma intermitente

Interrupter technique for evaluation of exercise-induced bronchospasm in children

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