Interrelationship between Metacarpal Bone Mass and Bone Mineral Content in Renal Transplant Recipients

Andresen, J; He, Nielsen

doi:10.1177/028418518202300513

Cited by 2 publications

(1 citation statement)

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“…Once the renal osteodystrophy has healed, the action of the ste roids is unopposed and may be potentiated by the com monly associated mild hyperparathyroidism. This might account for the findings of Andresen and Nielsen [1982] of a low bone density in patients 67 months after renal transplantation; the mean value of bone mineral concen tration of the radius and ulna was 25% below age-and sex-matched controls.…”

Section: Discussionmentioning

confidence: 80%

Changes in Total Body Calcium after Renal Transplantation: Effect of Low-Dose Steroid Regime

Eastell¹,

Kennedy²,

Smith³

et al. 1985

Nephron

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Total body calcium was measured in 8 men and 4 women, aged 20–51 years, undergoing kidney transplantation. The initial measurement was made within 8 weeks of operation and subsequent measurements up to 33 months postoperatively. Transplant rejection was prevented by low-dose prednisolone therapy (20 mg/day). 2 patients underwent parathyroidectomy for hypercalcaemia, and their total body calcium increased by 29 g (3%) and 66 g (8%). In the remainder the mean annual change was -0.9% (3.7, SD) over an average follow-up period of 17 months. This fall in total body calcium was statistically insignificant and was smaller than that previously described in patients treated with higher doses of steroids.

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Section: Discussionmentioning

confidence: 80%