Interpretation of Doppler signals

Grenier, N.; Basseau, F; Rey, Manuela; Lagoarde-Segot, Laurent

doi:10.1007/s003300100913

Cited by 13 publications

(8 citation statements)

References 19 publications

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“…Aortic and renal artery measurements were performed using a 3.5-MHz convex probe, while a 7.5-MHz linear probe was used in carotid artery measurements. Basal values of peak systolic flow velocity (V max ), end diastolic flow velocity (V min ), resistivity index (RI = V max -V min /V max ), and pulsatility index (PI = V max -V min / V mean ) [10] of the bilateral carotid and renal artery were determined by an experienced radiologist in awake dogs. Renal artery values were obtained from the main renal arteries and one segmental artery from each kidney.…”

Section: Methodsmentioning

confidence: 99%

Evaluation of the Effects of Sildenafil Citrate (Viagra) on Canine Renal Artery, Carotid and Aortic Blood Flow with the Aid of Color Doppler Sonography

Serhatlioğlu¹,

Kiris²,

Kocakoç³

et al. 2003

Urol Int

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Introduction: Erectile dysfunction is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. Oral use of sildenafil citrate has been proved to be effective in the treatment of erectile dysfunction. Although the effects of sildenafil citrate have been investigated in several studies, its effect on aortic, carotid and renal artery blood flow is unknown. The aim of this study was to investigate the early and late phase effects of sildenafil citrate on canine aortic, carotid and renal artery blood flow using color Doppler sonography (CDS). Materials and Methods: A total of 6 healthy adult dogs was used in this study. With the aid of CDS peak systolic flow rate, end diastolic flow rate, resistivity index (RI) and pulsatility index in aortic, renal and carotid artery were determined before the administration of sildenafil citrate, 45–75 min after drug administration and after 15 days of drug administration. Data were statistically analyzed using Friedman and Wilcoxon rank tests. p < 0.05 was considered to be statistically significant. Results and Conclusions: Significant changes were determined in only 4 out of 28 parameters studied. The significantly changed parameters were as follows: a significant increase in the early and late phase of the postdrug peak of systolic aortic blood flow compared to values before drug administration, an increase in pre- and postdrug RI values of the aorta, a significant decrease in maximum velocity of the right carotid artery, and peak systolic maximum velocity of the left renal segmental artery after drug administration compared to their respective predrug basal values. The results from this study indicate that sildenafil citrate has no significant effects on aortic, renal and carotid artery blood flow rate either in the early or in the late phase. Since this study involved only 6 dogs there is a need for further clinical studies involving larger groups of subjects to conclude that this drug is safe with respect to the hemodynamic parameters evaluated in this study.

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Section: Methodsmentioning

confidence: 99%

Evaluation of the Effects of Sildenafil Citrate (Viagra) on Canine Renal Artery, Carotid and Aortic Blood Flow with the Aid of Color Doppler Sonography

Serhatlioğlu¹,

Kiris²,

Kocakoç³

et al. 2003

Urol Int

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“…Combining color and spectral data, the Doppler signal provides physiologic information about arterial and venous hemodynamics and anatomic information about vessel walls and diameter. 2 It also allows noninvasive examination of blood flow velocities of the ophthalmic artery (OA) and its branches in the orbit. 3 In this study we evaluated the effect of antihypertensive therapy in patients with newly diagnosed essential hypertension with the use of the Doppler parameters of the central retinal artery (CRA), posterior ciliary artery (PCA), and OA.…”

mentioning

confidence: 99%

Effects of Hypertension and Antihypertensive Treatment on Retrobulbar Circulation Detected on Doppler Sonography

Karadeniz-Bilgili

Ekmekci

Köksal

et al. 2004

J of Ultrasound Medicine

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“…RI and PI are popular parameters for characterizing the arterial waveform on Doppler sonography. 9 In vitro and in vivo studies have shown that RI is related to vascular resistance.…”

Section: Discussionmentioning

confidence: 99%