Interoceptive control of blood coagulation

Essentially new inhibitors of metastasis of malignant tumors for chemotherapy-sparing treatment

“…Namely, fi brin occupies the main place in the mechanism of tumor metastasis. Histological studies have shown that the endothelium loses its normal structure when a tumor cell adheres to it in the form of a parietal thrombus [1,[3][4][5][6][7][8][9][10].…”

“…Most patients with malignant tumors die from metastases, which penetrate the vital organs and are diffi cult to respond to the defi nitive therapy. Therefore, the fi ght against tumor metastasis is the primary task of modern cancer chemotherapy [1][2][3][4][5][6][7][8][9][10].…”