“…Still, many patients with the persistent eosinophilic phenotype need low dose systemic glucocorticosteroids to maintain acceptable asthma control [67,68]. Unfortunately, chronic systemic glucocorticosteroid use has serious dose-and time-dependent side-effects, such as osteoporosis, diabetes, hypertension, cataract formation and myopathy [69,70]. Therefore, tapering oral glucocorticosteroids to the lowest effective dose is of high priority [69].…”