Internal Distribution and Absorbed Dose Calculations for Radioactive Indium Liver and Lung Scanning Agents

Brookeman, Valerie A.; Sun, Paul C. J.; Bruno, Fred P.; Dunavant, B.G.; Mauderli, Walter

doi:10.2214/ajr.109.4.735

Cited by 3 publications

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“…2,3 Carrier-free 113m ln in 2% gelatin (pH 4) is used for "vascular-pool" imaging applications. 4 113m In-labeled compounds can be used for lung and liver scanning, 5 and for brain imaging applications. 6 113 In can also be used as a radiotracer to study the flow behavior of crude oil in a battery of industrial crude oil/gas separators in oil industry.…”

Section: Introduction 99mmentioning

confidence: 99%

99Mo/99mTc-113Sn/113mIn Dual Radioisotope Generator Based on 6-Tungstocerate(IV) Column Matrix

Mostafa

El‐Sadek

El-Said

et al. 2009

Journal of Nuclear and Radiochemical Sciences

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Elutions of 99m Tc and 113m In have been performed subsequently with 10 mL of 0.9% NaCl solution and 10 mL of 0.1 M HCl solution, respectively, from 6-tungstocerate(IV) chromatographic column loaded with 0.54 MBq 99 Mo and 0.45 MBq 113 Sn, using alumina-column filter in the case of 99m Tc. Radionuclidic purity of both eluates was ≥ 99.99%. Elution yields of 72.5±5.8% and 62.2±3.7%, and radiochemical purities of 96.9±1.0% (as 99m TcO 4-) and 88.4±2.5% (as 113m In 3+) have been obtained for 99m Tc and 113m In, respectively. Al and W impurities in the 99m Tc and 113m In eluates, respectively, were found to be within the accepted limits, whereas no Ce impurities were detected in both eluates. Also trials have been carried out on a similar system to obtain mixed 99m Tc-113m In eluates from 6tungstocerate column with different 99m Tc/ 113m In ratios using 0.9% NaCl-HCl eluents of different pH values. To separate 99m Tc and 113m In from each other, these mixed eluates were passed through a column of hydrous zirconium oxide which was then eluted with 10 mL of 0.9% NaCl solution and 15 mL of 0.1 M HCl solution, respectively. No W, Ce, or Zr impurities were detected in the 99m Tc and 113m In eluates obtained in these trials.

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Section: Introduction 99mmentioning

confidence: 99%