Internal consistency of Waldrop Physical Anomaly Scale in schizophrenic patients

Akabaliev, Valentin H.; Sivkov, Stefan

doi:10.1016/j.psychres.2003.02.002

Cited by 19 publications

(13 citation statements)

References 9 publications

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“…These results may also substantiate that some genetic risk factors influencing liability to autism in males and females might act differently. Furthermore, in schizophrenia literature there are findings parallel to ours regarding a gender effect on the occurrence of morphological characteristics (McGrath et al 1995; Akabaliev and Sivkov 2007). …”

Section: Discussionsupporting

confidence: 83%

Morphological Features in Children with Autism Spectrum Disorders: A Matched Case–Control Study

Özgen

Hellemann

Stellato

et al. 2010

J Autism Dev Disord

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This study was designed to examine morphological features in a large group of children with autism spectrum disorder versus normal controls. Amongst 421 patients and 1,007 controls, 224 matched pairs were created. Prevalence rates and odds ratios were analyzed by conditional regression analysis, McNemar test or paired t-test matched pairs. Morphological abnormalities were significantly more prevalent in patients with autism than in the normal control group and 48 morphological features distinguished patients from controls. Our findings show that morphological features are associated with autism. Exploring potential underlying genetic mechanisms of this association might lead to a better understanding of autism.Electronic supplementary materialThe online version of this article (doi:10.1007/s10803-010-1018-7) contains supplementary material, which is available to authorized users.

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Section: Discussionsupporting

confidence: 83%

Morphological Features in Children with Autism Spectrum Disorders: A Matched Case–Control Study

Özgen

Hellemann

Stellato

et al. 2010

J Autism Dev Disord

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“…Results suggested moderate internal consistency form MPAs across body; the standardized alpha for the eight items was .56. However, it should be noted that the Waldrop and Halverson scale has been traditionally reported to have poorer internal consistency due to heterogeneity of anomalies in terms of location, character, and how MPAs relate to the timing of early developmental insults (Akabaliev & Sivkov, 2007; Compton et al, 2007; Sivkov & Akabaliev, 2003). This supports the importance of the present study, which is designed to elucidate developmental factors that the MPAs may be reflecting.…”

Section: Methodsmentioning

confidence: 99%

Minor physical anomalies and vulnerability in prodromal youth

Mittal

Walker

2011

Schizophrenia Research

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Because both the brain and craniofacial/limb features originate from the same germinal layer during early gestation, the postnatal presence of minor physical anomalies (MPAs) involving these physical features may be indicative of defects in prenatal neural migration and consequent brain abnormalities among individuals with psychosis. However, to date it is unknown what symptoms and characteristics MPAs may be associated with, or how these markers may reflect vulnerability among adolescents at high-risk for developing psychosis. This information is particularly vital for understanding susceptibility and informing etiological conceptualizations such as the neural diathesis-stress model. In this study, 50 adolescents with a prodromal syndrome were evaluated for MPAs, salivary cortisol, auditory and visual memory function, and attenuated positive, negative, and disorganized symptoms. Results indicated that the participants showing elevated MPAs (n = 25) were distinguished by elevated cortisol, deficit immediate and delayed visual memory, and higher levels of disorganized prodromal symptoms when compared with those participants exhibiting a lower incidence of MPAs. This was supported by supplementary correlational analyses examining the entire sample. These findings provide preliminary support for a theory that MPAs may reflect hippocampal system vulnerability among prodromal patients.

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“…As we (Trixler et al, 1997;Trixler and Tényi, 2000;Trixler et al, 2001;Tényi et al, 2009) and others (Akabaliev and Sivkov, 2007) have discussed earlier, a clear distinction between morphogenetic events developing during and after organogenesis is needed. Minor malformations are always abnormal and are qualitive defects of embryogenesis, which arise during organogenesis.…”

Section: Introductionmentioning

confidence: 91%

“…Once formed they persist into adult life and are readily detected on visual examination of the particular body area. Minor physical anomalies have been found with increased frequency in various neuropsychiatric illnesses (Waldrop and Goering, 1971;Méhes, 1988;Csábi et al, 2008), schizophrenia (Gualtieri et al,1982;Lohr and Flynn, 1993;Lane et al, 1997;Trixler et al, 1997Trixler et al, , 2001Akabaliev and Sivkov, 2007;Sivkov and Akabaliev, 2003;Weinberg et al, 2007) and affective disorders (Tényi et al, 2009). …”

Section: Introductionmentioning

confidence: 99%

Minor physical anomalies are more common in schizophrenia patients with the history of homicide

Tényi

Halmai²,

Antal³

et al. 2015

Psychiatry Research

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Internal consistency of Waldrop Physical Anomaly Scale in schizophrenic patients

Cited by 19 publications

References 9 publications

Morphological Features in Children with Autism Spectrum Disorders: A Matched Case–Control Study

Morphological Features in Children with Autism Spectrum Disorders: A Matched Case–Control Study

Minor physical anomalies and vulnerability in prodromal youth

Minor physical anomalies are more common in schizophrenia patients with the history of homicide

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