Intermittent low-magnitude high-frequency vibration promotes osteogenic protein expression and inhibits osteoclastogenic cytokine secretion in osteoblasts
Abstract:Background: Accumulating evidence has indicated that Low-Magnitude High-Frequency Vibration (LMHFV) can promote fracture healing, and thus, holds promise as a treatment for osteoporosis. However, few studies have reported the effects of LMHFV, especially intermittent LMHFV (iLMHFV) on osteoblasts in vitro. In this study, we examined the effects of sostenuto and intermittent LMHFV (sLMHFV and iLMHFV, respectively) on MC3T3-E1 preosteoblast proliferation and production of osteogenic and osteoclastogenic proteins… Show more
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