Interactive Effect of 6 Weeks of Aerobic Exercise and Quercetin Supplementation on TIE-2 and VEGF-A Expression in Tumor Tissue of Female Mice with Breast Cancer

Jalali, Zohreh; Shahidi, Fakhri

doi:10.30699/ijbd.14.3.46

ijbd

2021

DOI: 10.30699/ijbd.14.3.46

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Interactive Effect of 6 Weeks of Aerobic Exercise and Quercetin Supplementation on TIE-2 and VEGF-A Expression in Tumor Tissue of Female Mice with Breast Cancer

Zohreh Jalali

Fakhri Shahidi

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2024

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The interplay of exercise and polyphenols in cancer treatment: A focus on oxidative stress and antioxidant mechanisms

Wang

2024

Phytotherapy Research

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Exercise has been demonstrated to induce an elevated production of free radicals, leading to the onset of oxidative stress. Numerous studies highlight the positive impacts of aerobic exercise, primarily attributed to the increase in overall antioxidant capacity. The evidence suggests that engaging in aerobic exercise contributes to a reduction in the likelihood of advanced cancer and mortality. Oxidative stress occurs when there is an imbalance between the generation of free radicals and the collective antioxidant defense system, encompassing both enzymatic and nonenzymatic antioxidants. Typically, oxidative stress triggers the formation of reactive oxygen or nitrogen species, instigating or advancing various issues in cancers and other diseases. The pro‐oxidant‐antioxidant balance serves as a direct measure of this imbalance in oxidative stress. Polyphenols contain a variety of bioactive compounds, including flavonoids, flavanols, and phenolic acids, conferring antioxidant properties. Previous research highlights the potential of polyphenols as antioxidants, with documented effects on reducing cancer risk by influencing processes such as proliferation, angiogenesis, and metastasis. This is primarily attributed to their recognized antioxidant capabilities. Considering the extensive array of signaling pathways associated with exercise and polyphenols, this overview will specifically focus on oxidative stress, the antioxidant efficacy of polyphenols and exercise, and their intricate interplay in cancer treatment.

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The interplay of exercise and polyphenols in cancer treatment: A focus on oxidative stress and antioxidant mechanisms

Wang

2024

Phytotherapy Research

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Interactive Effect of 6 Weeks of Aerobic Exercise and Quercetin Supplementation on TIE-2 and VEGF-A Expression in Tumor Tissue of Female Mice with Breast Cancer

Cited by 1 publication

References 0 publications

The interplay of exercise and polyphenols in cancer treatment: A focus on oxidative stress and antioxidant mechanisms

The interplay of exercise and polyphenols in cancer treatment: A focus on oxidative stress and antioxidant mechanisms

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