“…Pancuronium (Yeh & Narahashi, 1977), N-alkylguanidines (Kirsch, Yeh, Farley & Narahashi, 1980) and gallamine (Smith & Schauf, 1981) are known to block the open-state of the voltagedependent sodium channel, resulting in acceleration of the decay of sodium current without affecting the rising phase of the current. As to calcium current (ICa), the inactivation process (the decay phase of ICa) has been analysed in various tissues, and ICa after reaching its peak, is inactivated in a voltage-and current-dependent manner (Kostyuk, Krishtal & Shakhovalov, 1977;Akaike, Lee & Brown, 1978;Brehm & Eckert, 1978;Tillotson, 1979;Brown, Morimoto, Tsuda & Wilson, 1981;Plant & Standen, 1981).…”