Interaction of chromium(III) or chromium(VI) with catalase and its effect on the structure and function of catalase: An in vitro study

Dermatologic Toxicities and Biological Activities of Chromium

“…Incubation of BALB/3 T3 clone A31 cells and HepG2 cells with chromium(III) chloride concentration higher than 400 μM would induce the formation of oxidative stress, while lower optimized concentration (M = 100-200 μM) would increase superoxide dismutase and catalase antioxidant activities [7]. In vitro study on the effect of chromium(III) and chromium(VI) on catalase activity also showed this dose-dependent activity in which treatment of cell-free catalase using chromium(III) (dose range 1-5 × 10 −5 mol/L) and chromium(VI) (dose range 1-4 × 10 −5 mol/L) separately increased the catalase activity [158]. These two studies clearly describe that either chromium(III) or chromium(VI) has a certain optimum concentration to exhibit their beneficial effects.…”

Cell cycle and transmembrane mitochondrial potential analysis after treatment with chromium(iii), iron(iii), molybdenum(iii) or nickel(ii) and their mixtures

“…30 It has been proved that chromium(III) at low concentrations statistically significantly increases superoxide dismutase and catalase activity, which are the most important enzymes involved in antioxidant activity. 31,32 This suggests that chromium(III) may activate antioxidant enzymes and protect against the toxic action of other metals. The catalase activity decreases at higher concentrations of Cr(III), which is probably caused by the destruction of an active site of catalase due to excess Cr(III).…”

Isolation and Identification of Chromium Reducing Bacillus Cereus Species from Chromium-Contaminated Soil for the Biological Detoxification of Chromium

“…The effect of pH (3,4,5,6,7,8,9, and 10) on the growth of the isolated strains was measured in a 100-well bacterial culture plate. The pH was adjusted by adding either 0.1 M HCl or 0.1 M NaOH as needed, which were tested in triplicate.…”

“…These untreated chromium-containing pollutants are mostly released into the environment, posing threats to ecosystems [2,5]. There are two common and stable oxidation states of chromium in the environment, namely Cr(VI) and Cr(III) [8][9][10]. Cr(III) is involved in sugar and lipid metabolism and is less toxic to humans [8,11,12], while Cr(VI) is carcinogenic, teratogenic, and mutagenic and is easily absorbed by humans through biomagnification in the food chain [13,14].…”