Interaction of 3′-azido-3′-deamino daunorubicin with human serum albumin: Investigation by fluorescence spectroscopy and molecular modeling methods

Interaction of 3′-azido-3′-deamino daunorubicin with DNA: Multispectroscopic and molecular modeling

“…In our previous research [16], a new daunorubicin analogue, 3 -azido-3 -deamino daunorubicin (ADNR, Fig. 1) was synthesized and the interaction of ADNR with human serum albumin (HSA) has been studied [17] which found that ADNR could bind to HSA and be effectively transported and eliminated in body.…”

Investigation on the toxic interaction of typical plasticizers with calf thymus DNA

“…Docking methods can provide visual representations of the interactions between the macromolecule and ligand, which can complement and substantiate the experimental results [29]. In recent years, this method has provided insight into the interactions between macromolecules and ligands with the help of docking programs such as Dock, AutoDock, Glide, and Surflexn [30][31][32][33][34].…”

Investigation of the Interaction between Nitrite Ion and Bovine Serum Albumin Using Spectroscopic and Molecular Docking Techniques

“…The ions affect the function of the protein by occupying the active site of albumin. [16][17][18][19][20][21] In this research, spectroscopic technologies including fluorescence spectroscopy, synchronous fluorescence spectroscopy, RRS and UV-Vis absorption spectroscopy were used to investigate the binding sites, modes, and forces for nitrite ion binding to BSA. Furthermore the binding sites and interaction of nitrite ion with BSA was studied with molecular modelling technique.…”

“…[15][16][17][18] A drug's efficiency may be affected by the degree to which it binds to the proteins within blood plasma. The less bound a drug is; the more efficiently it can traverse cell membranes or diffuse.…”