Abstract:The interaction which takes place a t room temperature between bacterial denatured DNA and ribosomal RNA has been studied by filtration on nitrocellulose filters and on Sephadex columns. The optimal conditions for this kind of interaction have been1determined. The melting curves and the effect of ribonuclease treatment are consistent with the hypothesis that in this kind of hybrids short base paired regions are present and unpaired RNA tails remain which are digested by ribonuclease. The average length of base… Show more
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