Intensive care unit-acquired hyponatremia in critically ill medical patients

Sim, Jae Kyeom; Ko, Ryoung Eun; Na, Soo Jin; Suh, Gee Young; Jeon, Kyeongman

doi:10.1186/s12967-020-02443-4

Cited by 17 publications

(12 citation statements)

References 18 publications

(52 reference statements)

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“…When dysnatremia is mild or moderate, clinical signs are often absent. And in the intensive care unit, the reasons for admission were not often the symptoms of dysnatremia [17].…”

Section: Discussionmentioning

confidence: 99%

Epidemio-clinical aspects of dysnatremia in polyvalent resuscitation at the CHU Antanambao Toliara

Rakotoniaina¹,

Ranaivosoa²,

Rakotovao-Ravahatra³

et al. 2022

World J. Bio. Pharm. Health Sci.

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Dysnatremia is common in hospitalized patients. This study aims to determine the prevalence of dysnatremia in the intensive care unit of the university hospital center Antanambao Toliara and to determine the diagnoses of the pathologies encountered in intensive care. This is a prospective, descriptive and cross-sectional analytical study over a period of six months from May 01, 2020 to October 31, 2020 carried out in the multipurpose intensive care unit at the Antanambao Toliara University Hospital. We selected 78 cases (27,87%) of dysnatremia. The average age was 43,30 years with a male predominance (sex ratio = 1,36). The disorder of consciousness was the first reason for admission of patients with dysnatremia (70.51%), followed by dyspnea (38.46%), postoperative (38.46%), fever (30. 77%), agitation (28.21%), edema (20.51%), seizure (10.26%), gastrointestinal bleeding (8.97%) and jaundice (5 ,13%). According to the diseases, 48 (61.54%) patients had medical pathologies and 30 (38.46%) surgical pathologies. Fever, sub or extra-durable hemorrhage, severe head trauma, hyperosmolar coma, gastric ulce and eclampsia had a significant association with dysnatrémie with p < 0,05. In brief, dysnatremia can be life-threatening in patients. Its early diagnosis therefore makes it possible to optimize the management of patients.

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“…When dysnatremia is mild or moderate, clinical signs are often absent. And in the intensive care unit, the reasons for admission were not often the symptoms of dysnatremia [17].…”

Section: Discussionmentioning

confidence: 99%

Epidemio-clinical aspects of dysnatremia in polyvalent resuscitation at the CHU Antanambao Toliara

Rakotoniaina¹,

Ranaivosoa²,

Rakotovao-Ravahatra³

et al. 2022

World J. Bio. Pharm. Health Sci.

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“…No primeiro caso, o plano terapêutico principal consiste na correção da volémia, através da administração de cloreto de sódio isotónico, enquanto nos outros casos (na sua maioria) é focado essencialmente na restrição de água (Darmon et al, 2014). Durante todo o processo, além dos níveis de sódio, deve ser monitorizada a função renal (Sim et al, 2020).…”

Section: Discussionunclassified

Infocovid: Informações Científicas Sobre Covid-19 Nas Redes Sociais

Cruz¹,

Modesto²,

MAZZA³

et al. 2021

A Enfermagem a Partir De Uma Visão Crítica: Excelência Das Práticas De Cuidado 2

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“…Hypernatremia is routinely detected in intensive care units (ICUs) [1][2][3][4] and more frequently in the neurosurgical ICU than in the general ICU [3]. Hypernatremia may be associated with various complications in critically ill patients [3][4][5][6][7]. Therefore, ICUacquired hypernatremia is associated with poor clinical outcomes in critically ill patients [1,4,6,8].…”

Section: Introductionmentioning

confidence: 99%

Clinical Outcomes Associated with Degree of Hypernatremia in Neurocritically Ill Patients

Lee¹,

Ahn

Ryu

2021

Preprint

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Background: Hypernatremia is a common complication encountered during the treatment of neurocritically ill patients. However, it is unclear whether clinical outcomes correlate with the severity of hypernatremia in such patients. Therefore, we investigated the impact of hypernatremia on mortality of these patients, depending on the degree of hypernatremia.Methods: Among neurosurgical patients admitted to the intensive care unit (ICU) in a tertiary hospital from January 2013 to December 2019, patients who were hospitalized in the ICU for more than 5 days and whose serum sodium levels were obtained during ICU admission were included. Hypernatremia was defined as the highest serum sodium level exceeding 150 mEq/L observed. We classified the patients into four subgroups according to the severity of hypernatremia and performed propensity score matching analysis.Results: Among 1,146 patients, 353 patients (30.8%) showed hypernatremia. Based on propensity score matching, 290 pairs were included in the analysis. The hypernatremia group had higher rates of in-hospital mortality and 28-day mortality in both overall and matched population (both p < 0.001 and p = 0.001, respectively). In multivariable analysis of propensity score-matched population, moderate and severe hypernatremia were significantly associated with in-hospital mortality (adjusted odds ratio [OR]: 4.58, 95% confidence interval [CI]: 2.15 – 9.75 and adjusted OR: 6.93, 95% CI: 3.46 – 13.90, respectively) and 28-day mortality (adjusted OR: 3.51, 95% CI: 1.54 – 7.98 and adjusted OR: 10.60, 95% CI: 5.10 – 21.90, respectively) compared with the absence of hypernatremia. However, clinical outcomes, including in-hospital mortality and 28-day mortality, were not significantly different between the group without hypernatremia and the group with mild hypernatremia (p = 0.720 and p = 0.690, respectively). The mortality rates of patients with moderate and severe hypernatremia were significantly higher in both overall and matched population. Interestingly, the mild hypernatremia group of matched population showed the best survival rate.Conclusions: Moderate and severe hypernatremia were associated with poor clinical outcomes in neurocritically ill patients. However, the prognosis of patients with mild hypernatremia was similar with that of patients without hypernatremia. Therefore, mild hypernatremia may be allowed during treatment of intracranial hypertension using hyperosmolar therapy.

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Intensive care unit-acquired hyponatremia in critically ill medical patients

Cited by 17 publications

References 18 publications

Epidemio-clinical aspects of dysnatremia in polyvalent resuscitation at the CHU Antanambao Toliara

Epidemio-clinical aspects of dysnatremia in polyvalent resuscitation at the CHU Antanambao Toliara

Infocovid: Informações Científicas Sobre Covid-19 Nas Redes Sociais

Clinical Outcomes Associated with Degree of Hypernatremia in Neurocritically Ill Patients

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