Intensity-modulated radiotherapy of the prostate: Dynamic ADC monitoring by DWI at 3.0T

Decker, G. Anton; Mürtz, Petra; Gieseke, Jürgen; Träber, Frank; Block, Wolfgang; Sprinkart, Alois M.; Leitzen, Christina; Buchstab, Timo; Lütter, Christiana; Schüller, Heinrich; Schild, Hans H.; Willinek, Winfried A.

doi:10.1016/j.radonc.2014.07.016

Cited by 49 publications

(42 citation statements)

References 27 publications

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“…The report that how FDG-PET and MRI reflected for effect of treatment in the diagnosis instrument of these days came to be accomplished [4][5][6]. When the increase of the ADC level of the site where prostate cancer is present in significantly correlated with a decrease of the PSA according to the report of Yamaguchi et al in DWI the radiotherapy half a year later, we report it [1].…”

Section: Discussionmentioning

confidence: 73%

Influence of fiducial marker for MR image of prostate radiotherapy

Tanaka¹,

Komeda²,

Hirose³

et al. 2018

Intergr Clin Med

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Fiducial marker for registration to CT and MRI in intensity modulated radiation therapy for prostate cancer came to be increasing. Whereas diffusion weighted image came to be used similar to the PSA of the blood test for radiotherapy effect measurement for prostate cancer. Generally, the diffusion weighted image was often affected by a magnetic component.We evaluated how much the marker had an influence on the diffusion weighted image. As a result, it was degree in range 2-5 mm that detained a marker that marker affected the image. We concluded that a fiducial marker does not affect the quality of diffusion weighted image on daily practice.

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Section: Discussionmentioning

confidence: 73%

Influence of fiducial marker for MR image of prostate radiotherapy

Tanaka¹,

Komeda²,

Hirose³

et al. 2018

Intergr Clin Med

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“…Diffusion MRI sequences have been shown to predict response to RT [86,87] earlier than gross tumor size changes or metabolic changes based on FDG PET-CT [88]. Both the baseline apparent diffusion coefficient (ADC) and changes in ADC, specifically increase in ADC after RT, correlate with tumor control and patient outcome after radiotherapy [89][90][91][92][93][94]. The UCLA group recently published the results of a pilot study utilizing a spin echo-based diffusion sequence on the tri- 60 Co system to track changes in diffusion over the course of RT for six patients [95].…”

Section: Adaptive Radiotherapymentioning

confidence: 99%

MRI-guided radiotherapy: Opening our eyes to the future

Kishan¹,

Lee²

2016

Integr Cancer Sci Therap

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When discussing local treatment modalities, physicians often quip that there can be no blind surgeons, suggesting that an inherent advantage to surgery is the ability to precisely visualize the target. Advances in radiation therapy (RT) technology over the years have significantly improved the radiation oncologists' abilities to precisely sculpt high-dose radiation to a variety of targets, simultaneously improving local control and toxicity profiles. However, even the most sophisticated methods of CT-based image-guided radiotherapy (IGRT) are hampered by limitations that can compromise target localization and motion management. Additionally, realtime adaptive radiotherapy (ART) programs, wherein radiation plans can be molded to fit the often malleable anatomy of tumors and organs-at-risk, have not yet been developed. For these reasons, MRI-guided RT is considered the next frontier of radiation oncology. However, the development of integrated MRI/RT-delivery platforms is complicated by several technical challenges that have precluded development of MRI-guided linear accelerators. By virtue of employing a low-field (0.35 T) MRI and three 60 Co sources, a newly available tri-60 Co teletherapy system (MRIdian System™, ViewRay™, Cleveland, OH, USA) has tackled these technical concerns and has thus become the first MRI-guided RT platform with FDA approval for medical use. In this Review, we describe the abilities of this device to accomplish the goals of MRI-guided RT-improved target localization, sophisticated motion management, and on-line ART-by exploring published feasibility, proof-of-principle, and proof-of-practice studies.

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“…Under external radiotherapy of the prostate, the ADC value in carcinomas of the prostate increases significantly but does not change substantially in healthy prostate tissue [27]. DCE-MRI: DCE-MRI includes the fast acquisition of T1w sequences after bolus application of a gadolinium-containing contrast agent and is established in clinical oncology as a biomarker [28].…”

Section: Dwi Dce-mri 1 H-mrsmentioning

confidence: 99%

“…By using a combined endorectal body phased-array coil, the sensitivity and the positive predictive value for the detection of prostate cancer could be increased in individual studies even in 3 T MRI examinations [27]. The sole use of a body phased-array coil at 3 T as widely used in practice is justified by the good detection of significant tumors [28].…”

Section: Endorectal Coilmentioning

confidence: 99%

MRT der Prostata: Empfehlungen zur Vorbereitung und Durchführung

Franiel

Quentin

Mueller‐Lisse³

et al. 2016

Fortschr Röntgenstr

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The Working Group Uroradiology and Urogenital Diagnosis of the German Roentgen Society has developed uniform recommendations for the preparation and implementation of prostate MRI. In the first part detailed recommendations are given in tabular form regarding 1. anamnestic data before prostate MRI, 2. termination of examinations and preparation of examinations, 3. examination protocol and 4. MRI-guided in-bore biopsy. In the second part, the recommendations are discussed in detail and relevant background information is provided. Key Points: Citation Format

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Intensity-modulated radiotherapy of the prostate: Dynamic ADC monitoring by DWI at 3.0T

Cited by 49 publications

References 27 publications

Influence of fiducial marker for MR image of prostate radiotherapy

Influence of fiducial marker for MR image of prostate radiotherapy

MRI-guided radiotherapy: Opening our eyes to the future

MRT der Prostata: Empfehlungen zur Vorbereitung und Durchführung

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