Intensity Analysis of Hartmann-Shack Images in Cataractous, Keratoconic, and Normal Eyes to Investigate Light Scattering

Mihashi, Toshifumi; Hirohara, Yoko; Bessho, Kenichiro; Maeda, Naoyuki; Oshika, Tetsuro; Fujikado, Takashi

doi:10.1007/s10384-006-0336-y

Cited by 23 publications

(21 citation statements)

References 28 publications

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“…8 Light scattering due to small water particles is caused by Mie scattering that propagates backward and forward. 15 The backward light scattering by the small water aggregates can be observed as surface light scattering. Further analysis of the extracted IOL is required to assess the etiology.…”

Section: Discussionmentioning

confidence: 99%

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Effect on visual acuity of increased surface light scattering in intraocular lenses

Miyata¹,

Honbo²,

Otani³

et al. 2012

Journal of Cataract and Refractive Surgery

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Section: Discussionmentioning

confidence: 99%

“…Forward light scattering predominantly contributes to the contrast sensitivity and visual acuity. 18 Evaluation of forward scattering using a Hartmann-Shack wavefront analyzer 15,18 or a double-pass optical analyzer 19 is required. The exclusion criteria used to analyze the change in visual acuity is also a limitation.…”

Section: Discussionmentioning

confidence: 99%

Effect on visual acuity of increased surface light scattering in intraocular lenses

Miyata¹,

Honbo²,

Otani³

et al. 2012

Journal of Cataract and Refractive Surgery

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“…The magnitude of increased wavefront aberration associated with TBU, as quantified by the RMS of the modal wavefront, is consistent with the literature. 1,4,6-9,39 The modal WFE map is the sum of two other maps (LOA, HOA) displayed in the third and fourth rows. The VHOA map displayed in the fifth row is the difference between the zonal and modal maps.…”

Section: Resultsmentioning

confidence: 99%

Scale and Spatial Distribution of Aberrations Associated with Tear Breakup

Himebaugh¹,

Nam²,

Bradley³

et al. 2012

Optometry and Vision Science

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Purpose We examined the spatial correlation between tear break up (TBU) and the associated optical anomalies on multiple spatial scales. Methods Five subjects refrained from blinking while the time course and patterns of TBU were sequentially observed using fluorescein (FL), retroillumination (RI), and Shack-Hartmann (SH) aberrometry. Wavefront error maps were developed using Zernike polynomials, as well as local zonal analysis of measured wavefront slopes. The difference between these maps reveals the presence of very high order aberrations missed by standard modal fitting methods. Size of SH spots was also quantified to estimate optical perturbations on a microscopic scale. The spatial correlation between TBUand optical aberrations was also computed. Results Degradation of the tear film increased wavefront aberrations over all spatial scales measured. Consistent with tear thinning, blink suppression induced an irregular pattern of phase advances in regions of TBU. SH spot size also increased in regions of TBU, which indicates the presence of optical aberrations on a scale smaller than individual lenslets. Conclusions The optical signature of TBU caused by blink suppression is a combination of wavefront aberrations on macroscopic and microscopic scales due to nonuniform tear film thinning and possible exposure of a rough epithelial surface. Localized optical 2 defects correspond temporally and spatially with TBU revealed by FL and RI. In addition to gross wavefront aberrations, scatter develops in areas of TBU that will further contribute to image degradation and visual disturbances following TBU.

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“…The source of the light scattering is small particles ofwhich size is about one gm [21]. But we found very narrow angle scattering from cataractous eyes [22]. Optical characteristics to cause this narrow angle scattering may be related to the different PCs ofcataractous eyes from those ofnormal eyes.…”

Section: Disscusionmentioning

confidence: 98%

Aberration Structure of Normal, Keratoconic, and Cataractous Eyes

Mihashi

Hirohara

Maeda

et al. 2007

2007 IEEE/ICME International Conference on Complex Medical Engineering

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Recently aberrometry of the eye is a popular topic in the ophthalmology and optometry fields. The most popular method of the aberrometry is the Shack-Hartmann method which successfully measures various pathological eyes in the clinic. By combining it with the corneal topography, we found interesting aberration structures in keratoconic and cataractous eyes. We analyzed those eye using principal component analysis.

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Intensity Analysis of Hartmann-Shack Images in Cataractous, Keratoconic, and Normal Eyes to Investigate Light Scattering

Abstract: The two methods introduced here successfully distinguished cataractous eyes from normal and keratoconic eyes. After the results were analyzed by a discriminant analysis, the separation of the three categories proved to be excellent.

Cited by 23 publications

References 28 publications

Effect on visual acuity of increased surface light scattering in intraocular lenses

Effect on visual acuity of increased surface light scattering in intraocular lenses

Scale and Spatial Distribution of Aberrations Associated with Tear Breakup

Aberration Structure of Normal, Keratoconic, and Cataractous Eyes

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