Intense pulsed light therapy for the treatment of evaporative dry eye disease

Vora, Gargi K.; Gupta, Preeya K.

doi:10.1097/icu.0000000000000166

Cited by 115 publications

(126 citation statements)

References 23 publications

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“…Figures and illustrate the gradual improvement across the 12 weeks of monitoring. Therefore, our prospective results support previous observations in retrospective chart reviews of the cumulative and sustained (at least in the short term) effect of intense pulsed light and MGX to treat moderate to advanced MGD.…”

Section: Discussionsupporting

confidence: 89%

“…Therapeutic MGX was an uncomfortable procedure, even when performed with topical anaesthesia . As some degree of temporary lid margin and conjunctival injection was induced following MGX in all participants and as per previous studies involving therapeutic expression, preservative‐free topical anti‐inflammatory (two drops, prednisolone sodium phosphate 0.5 per cent, minim form, Bausch + Lomb) was instilled immediately following expression. All treatments were performed on both eyes by one operator.…”

Section: Methodsmentioning

confidence: 99%

“…The device and the nature of the light it emits have been reviewed . Following reports that serial periocular intense pulsed light treatments improve signs and symptoms of dry eyes in individuals with acne rosacea and ocular surface disease, the clinical application of intense pulsed light devices have been extended to include the treatment of MGD …”

mentioning

confidence: 99%

“…The emerging clinical data regarding the safety and efficacy of intense pulsed light treatment for MGD suggests that a series of two or more intense pulsed light treatments can improve symptoms, tear film characteristics, including tear film break‐up time and clinical signs of MGD; however clinical guidelines regarding candidate selection, the number and frequency of treatments and the efficacy of post‐intense pulsed light meibomian gland expression (MGX) are yet to be established. At the time of writing, of the five published studies assessing the efficacy of intense pulsed light as a treatment for MGD, three were retrospective reviews of treatment series involving individuals with moderate to advanced MGD treated with the Quadra Q4 (DermaMed Solutions, LLC, Lenni, Pennsylvania, USA) intense pulsed light system using a proprietary ‘dry eye mode’ setting.…”

mentioning

confidence: 99%

“…At the time of writing, of the five published studies assessing the efficacy of intense pulsed light as a treatment for MGD, three were retrospective reviews of treatment series involving individuals with moderate to advanced MGD treated with the Quadra Q4 (DermaMed Solutions, LLC, Lenni, Pennsylvania, USA) intense pulsed light system using a proprietary ‘dry eye mode’ setting. Intense pulsed light was applied both inferior and lateral to both lower eyelids followed by MGX using a fingertip or cotton tip applicator . A fourth published study was a prospective, double‐masked, placebo‐controlled, paired‐eye study involving the application of the E > Eye (E‐Swin, Paris, France), an intense pulsed light device regulatory approved in Australia and New Zealand for treating MGD .…”

mentioning

confidence: 99%

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Intense pulsed light treatment and meibomian gland expression for moderate to advanced meibomian gland dysfunction

Albietz

Schmid

2018

Clinical and Experimental Optometry

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Background:The aim was to evaluate the efficacy of periocular intense pulsed light therapy combined with meibomian gland expression for chronic dry eye due to moderate to advanced meibomian gland dysfunction. Conclusions: Serial intense pulsed light therapy combined with meibomian gland expression significantly improved dry eye symptoms and clinical signs, including meibomian gland secretion quality and expressibility and ocular surface inflammation. Treatment effects were cumulative and sustained for at least six weeks after the final treatment.

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Section: Discussionsupporting

confidence: 89%

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Intense pulsed light treatment and meibomian gland expression for moderate to advanced meibomian gland dysfunction

Albietz

Schmid

2018

Clinical and Experimental Optometry

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Ocular rosacea: The often‐overlooked component of rosacea

Geng,

Slomovic,

Bourkas

et al. 2024

JEADV Clinical Practice

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Ocular rosacea is a chronic inflammatory condition that affects the eyes and periocular skin as part of the broader cutaneous rosacea skin disease. Cutaneous rosacea is common, affecting approximately 5.5% of the global population, where up to 72% of patients will develop ocular involvement either before or after the cutaneous disease. Clinical features of ocular rosacea include Meibomian gland disease, blepharitis and conjunctivitis. Ocular rosacea reduces quality of life through various potential mechanisms including anxiety, social withdrawal and physical discomfort. If left untreated, ocular rosacea can reduce visual acuity and in severe cases, vision loss. Several topical and systemic treatment options are available, with efficacies based on their anti‐inflammatory properties. This review focuses on the clinical features of ocular rosacea, differential diagnoses and treatment options with the aim of aiding clinicians involved in the care of rosacea patients to better identify onset of the ocular manifestations of rosacea and prevent its severe complications.

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