Integration of gold nanoparticles in PDMS microfluidics for lab-on-a-chip plasmonic biosensing of growth hormones

Saberi, Hamid; Bădilescu, Simona; Packirisamy, Muthukumaran; Wüthrich, Rolf

doi:10.1016/j.bios.2013.01.016

Cited by 132 publications

(83 citation statements)

References 37 publications

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“…An alternative way to prepare AuNPs was proposed by SadAbadi et al [93] using PDMS microchannels; and afterwards, the device was used as a sensitive and low-cost localized surface plasmon resonance (SPR)-based biosensor for the detection of polypeptides. The biosensing experiment was based on the detection of antigen-antibody interaction of bovine growth hormones through the measurement of localized SPR spectra of the samples.…”

Section: Gold Nanoparticlesmentioning

confidence: 99%

Utilisation of micro- and nanoscaled materials in microfluidic analytical devices

Monošík

Angnes

2015

Microchemical Journal

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Section: Gold Nanoparticlesmentioning

confidence: 99%

Utilisation of micro- and nanoscaled materials in microfluidic analytical devices

Monošík

Angnes

2015

Microchemical Journal

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“…It is estimated that the global biochips market will increase from $3.3 billion in year 2012 to $14.4 billion by year 2018, with a compound annual growth rate of 30 % [360]. Due to nanoparticles' unique characteristics, they are often used in lab-on-achip products for various functions, such as property improver, catalyst, sensing, imaging, and as a carrier [145,258,348,371,417]. For example, in a microfluidic-based chip for early detection of HIV and syphilis, Au nanoparticles are used as carriers and labelers for antibodies and also a substrate for Ag reduction, as shown in Fig.…”

Section: Biomedicinementioning

confidence: 99%

Application of Nanoparticles in Manufacturing

Hu¹,

Tuck²,

Wildman³

et al. 2015

Handbook of Nanoparticles

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With the development of nanoscience and nanotechnology, manufacturing is undergoing revolutionary changes. Nanoparticles, due to their novel and often enhanced properties, are now more and more used in manufacturing. In this chapter, the state-of-the-art application of nanoparticles in manufacturing is reviewed. The contents include five parts: (a) role of nanoparticles in manufacturing, (b) manufacturing methods, (c) applications, (d) challenges, and (e) conclusions. The roles of nanoparticles are divided into three categories: (i) building blocks, being the major component of a manufactured product by solid-state or colloidal nanoparticle consolidation; (ii) functional filler, as an addition for functionality, such as property improver, catalyst, stimuli-responsive, sensing, imaging, and carrier; and (iii) nanocomposites for multifunctionality. Various manufacturing methods and novel trends are summarized in this chapter, including top-down and bottom-up, from 2D to 3D, from cleanroom to desktop, 3D printing, and bio-assisted methods, such as DNA origami. Direct applications in areas of flexible electronics, molecular electronics, solar cells, construction industry, water treatment, and biomedical devices are presented. The associated challenges including nanoparticle safety issue, sustainable manufacturing, economic issue, and scale-up are discussed. Role of Nanoparticles in ManufacturingWith the development of nanoscience and nanotechnology, manufacturing is undergoing revolutionary changes. Nanoparticles, due to their novel and often enhanced properties, have more and more been used in various manufacturing applications. Their role can generally be divided into three categories: (a) building blocks, (b) functional filler, and (c) nanocomposites for multifunctionality, which is summarized in Table 1. Building BlockNanoparticles sometimes act like the bricks in a house-building process to be the main component of a manufactured product. They can be consolidated via solid-and liquid-based methods. Solid-State Nanoparticle ConsolidationSolid-state metallic, ceramic, amorphous, and compound particles can be thermomechanically processed to form bulk 2D/3D structures with desired strength and level of densification (even full densification is possible). Reported methods include powder compact forging/extrusion, equal channel angular extrusion/ pressing, and hot pressing/sinter forging combined with conventional heating, laser sintering, microwave sintering, electric discharge sintering, or spark plasma sintering [33,255,278,306,425,426,476,492]. Particles with a narrow size distribution and spherical shape are desired to achieve low pore-to-

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“…As can be seen, synthesis of metal NPs starts with a metal containing salt solution and a reducing agent, although sometimes the reducing agent is not needed. 22,23 Thereafter, usually ligands or surfactants, the so-called capping agents, are used to control the shape and size of the structures. The type and mode of mixing of these ligands have a great influence on the final shape and composition of the NPs.…”

Section: Introductionmentioning

confidence: 99%

Microfluidics and catalyst particles

et al. 2019

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In this review article, we discuss the latest advances and future perspectives of microfluidics for micro/ nanoscale catalyst particle synthesis and analysis. In the first section, we present an overview of the different methods to synthesize catalysts making use of microfluidics and in the second section, we critically review catalyst particle characterization using microfluidics. The strengths and challenges of these approaches are highlighted with various showcases selected from the recent literature. In the third section, we give our opinion on the future perspectives of the combination of catalytic nanostructures and microfluidics. We anticipate that in the synthesis and analysis of individual catalyst particles, generation of higher throughput and better understanding of transport inside individual porous catalyst particles are some of the most important benefits of microfluidics for catalyst research. SynthesisThis section focuses on the most recent approaches within the last 8 years. For a more extensive overview of the synthesis of nanostructures focused on the processes taking place inside the microfluidic systems, 5 the final application 4 or the microfluidic technology used 6,7 we refer the reader to other review articles. Metal nanoparticlesMetal nanoparticles exhibit very interesting catalytic, optical, chemical, electromagnetic and magnetic properties, all of them depending to a large degree on their size and composition. Regarding catalysis, a decrease of the NP size leads to a surface-area increase per mass, providing more active sites. Also, the surface structure is of vital importance for the NP selectivity: the presence of steps, edges or terraces in the atomic surface can influence the reaction pathways to Lab Chip, 2019, 19, 3575-3601 | 3575 This journal is

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Integration of gold nanoparticles in PDMS microfluidics for lab-on-a-chip plasmonic biosensing of growth hormones

Cited by 132 publications

References 37 publications

Utilisation of micro- and nanoscaled materials in microfluidic analytical devices

Utilisation of micro- and nanoscaled materials in microfluidic analytical devices

Application of Nanoparticles in Manufacturing

Microfluidics and catalyst particles

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