Integrating Screening and Treatment of Unhealthy Alcohol Use and Depression with Screening and Treatment of Anxiety, Pain, and Other Substance Use Among People with HIV and Other High-Risk Persons

Khan, Maria R.; Ban, Kaoon; Braithwaite, R. Scott

doi:10.1007/s10461-021-03245-5

Cited by 16 publications

(12 citation statements)

References 52 publications

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“…Caniglia et al proposed that screening and treatment for alcohol and depression may help alleviate comorbidity of anxiety, other substance abuse, etc. in PLWH ( Caniglia et al, 2021 ). It’s time to incorporate screening and detox for alcohol, drugs, and cocaine into routine clinical care for HIV, especially the management of alcohol in men ( Lancaster et al, 2021 ; Maisto et al, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

Global trends in depression among patients living with HIV: A bibliometric analysis

Zhang

Hao

et al. 2023

Front. Psychol.

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BackgroundHuman immunodeficiency virus (HIV) related depression has seriously affected the quality of life and treatment outcomes of patients living with HIV (PLWH), which has become a hot topic in recent years. This study aims to discover the main keywords, predict frontier topics, and give meaningful suggestions for researchers by bibliometric analysis.MethodsPublications between 1999 and 2022 on depression in HIV/AIDS were searched in the Web of Science core collection. Microsoft Excel 2010 and VOSviewer were utilized to key contributors (e.g., authors, journals, institutions, and countries). VOSviewer and CiteSpace were used to analyze the knowledge evolution, collaborative maps, hot topics, and keywords trends in this field.ResultsIn total, 8,190 publications were included in the final analysis. From 1999 to 2021, the number of published articles roughly presents a steadily increasing trend. The United States, South Africa, and the United Kingdom were three key contributing countries/regions to this field. University Calif San Francisco (United States), University Calif Los Angeles (United States), and Johns Hopkins University (United States) were three key contributing institutions. Safren, Steven A. was the most productive and highest cited author. AIDS Care was the top prolific journal. Antiretroviral therapy and adherence, men has sex with men, mental health, substance abuse, stigma, and Sub-Saharan Africa were the central topics regarding the depression-related research in HIV/AIDS.ConclusionThis bibliometric analysis reported the publication trend, major contributing countries/regions, institutions, authors, journals and mapped the knowledge network of depression-related research on HIV/AIDS. In this field, topics such as “adherence,” “mental health,” “substance abuse,” “stigma,” “men who have sex with men” and “South Africa” have attracted considerable attention.

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Section: Discussionmentioning

confidence: 99%

Global trends in depression among patients living with HIV: A bibliometric analysis

Zhang

Hao

et al. 2023

Front. Psychol.

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“…Finally, we simulated the influence of screening for alcohol, depression, and tobacco and conducting a comprehensive diagnostic assessment and treatment of all psychiatric and substance use conditions (depression, anxiety, pain, and alcohol, marijuana, illicit opioid, and stimulant use), given the strong clustering of these conditions. 18 To assess LE gains, we compared each screening/ decarceration scenario to a counterfactual assuming 100% of cohort members would be exposed to incarceration, and no additional CASM screening would occur. LE differences between each intervention scenario and the counterfactual arose from the following modeled effects: health benefits from improvements in CASM conditions due to decarceration and health benefits from improvements in CASM conditions that were treated.…”

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

“…Previous research suggests that screening co-occurring unhealthy alcohol use, substance use, and mental disorders (CASM), with linkage to diagnostic assessment and treatment for conditions diagnosed as positive, could have substantial health benefits among people without HIV and even larger benefits among people living with HIV (PLHIV) because of the way these conditions affect one another and, in PLHIV, impact adherence to treatment. 18 It is likely that the benefits of CASM screening and treatment would be especially profound among BSMM/BTW with HIV with a risk of incarceration because of the high prevalence and strong interrelationships among these conditions and their impact on HIV treatment success. However, research on how improved screening for these conditions in the clinical setting and how they could influence LE for BSMM/BTW with a history of incarceration is limited.…”

Section: Introductionmentioning

confidence: 99%

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Impact of Decarceration Plus Alcohol, Substance Use, and Mental Health Screening on Life Expectancies of Black Sexual Minority Men and Black Transgender Women Living With HIV in the United States: A Simulation Study Based on HPTN 061

Feelemyer,

Bershteyn,

Scheidell

et al. 2024

JAIDS Journal of Acquired Immune Deficiency Syndromes

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Background Given the disproportionate rates of incarceration and lower life expectancy (LE) among Black sexual minority men (BSMM) and Black transgender women (BTW) with HIV, we modeled the impact of decarceration and screening for psychiatric conditions and substance use on LE of US BSMM/BTW with HIV. Methods We augmented a microsimulation model previously validated to predict LE and leading causes of death in the US with estimates from the HPTN 061 cohort and the Veteran’s Aging Cohort Studies. We estimated independent associations among psychiatric and substance use disorders, to simulate the influence of treatment of one condition on improvement on others. We used this augmented simulation to estimate LE for BSMM/BTW with HIV with a history of incarceration under alternative policies of decarceration (i.e., reducing the fraction exposed to incarceration), screening for psychiatric conditions and substance use, or both. Results Baseline LE was 61.3 years. Reducing incarceration by 25%, 33%, 50%, and 100% increased LE by 0.29 years, 0.31 years, 0.53 years, and 1.08 years, respectively, versus no reductions in incarceration. When reducing incarceration by 33% and implementing screening for alcohol, tobacco, substance use, and depression, in which a positive screen triggers diagnostic assessment for all psychiatric and substance use conditions and linkage to treatment, LE increased by 1.52 years compared to no screening or decarceration. Discussion LE among BSMM/BTW with HIV is short compared with other people with HIV. Reducing incarceration and improving screening and treatment of psychiatric conditions and substance use could substantially increase LE in this population.

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“…Adrawa et al also showed an association between alcohol use and non-adherence in community-based ART distribution settings in Uganda, with participants attributing forgetfulness as a major cause of nonadherence (47). Available data suggest that addressing mental health problems by early screening and interventions at the time of counseling, testing, ART initiation, and follow-up care may be critical for better outcomes for PWH (48, 49, 50).…”

Section: Introductionmentioning

confidence: 99%

Mental disorders and adherence to antiretroviral treatment in health facilities in Mozambique

Mandlate

Green

Pereira

et al. 2022

Preprint

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Introduction: Less adherence to antiretroviral treatment (ART) has been found among people suffering from HIV (PWH) with comorbid mental disorders like depression and alcohol use in Mozambique, a Sub-Saharan African country. However, less is explored with regards to other mental disorders. Methods: This study assessed the association of multiple mental disorders and adherence to ART based on the data from primary/tertiary health care facilities in Maputo and Nampula, Mozambique. We administered a sociodemographic questionnaire, Mini International Neuropsychiatric Interview (MINI) Plus 4.0.0 adapted for use in Mozambique to assess mental conditions, and a 3-item self-report to measure ART adherence. Results: Out of 1469 participants, 409 were HIV positive (self-report), with an average age of 36.7 years (SD=9.8), and 30.4% were male. The most common mental disorders were major depressive disorder (27.34%) followed by psychosis (22.03%), suicidal ideation/behavior (15.44%), and alcohol-use disorder (8.35%). Higher levels of non-adherence to ART [(Mean Difference=1.19, 95% CI: 1.04, 1.37)] and the likelihood of missing at least one dose in the last 30 days (OR=3.06, 95% CI: 2.00, 4.67) were found in participants with any mental disorder compared to those without a mental disorder. The highest levels of non-adherence were observed among those with drug use disorders and panic disorder. Conclusions: In Mozambique, PWH with any co-occurring mental conditions had a lower probability of ART adherence. Integrating comprehensive mental health assessment and treatment and ART adherence interventions tailored to PWH with co-occurring mental disorders is necessary to attain optimal ART adherence and reach the UNAIDS ART target. Keywords:Mental disorders, ART adherence, HIV/AIDS treatment, Mozambique

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Integrating Screening and Treatment of Unhealthy Alcohol Use and Depression with Screening and Treatment of Anxiety, Pain, and Other Substance Use Among People with HIV and Other High-Risk Persons

Cited by 16 publications

References 52 publications

Global trends in depression among patients living with HIV: A bibliometric analysis

Global trends in depression among patients living with HIV: A bibliometric analysis

Impact of Decarceration Plus Alcohol, Substance Use, and Mental Health Screening on Life Expectancies of Black Sexual Minority Men and Black Transgender Women Living With HIV in the United States: A Simulation Study Based on HPTN 061

Mental disorders and adherence to antiretroviral treatment in health facilities in Mozambique

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