AIMS: To identify the perception of nursing students about the structural dimensions of the design of high-fidelity simulation scenarios in adult immunization scenarios in the context of primary health care.METHODS: Descriptive, exploratory, quantitative study developed at a Brazilian federal public university from May to June 2017. The final sample consisted of 17 students. The 5-item Likert simulation design Scale was used to evaluate the design of simulation scenarios.RESULTS: The majority of students are young and female adults (82.4%). In the internal consistency analysis, the simulation design scale presented a total Cronbach's alpha of 0.930. In all dimensions of the scale, overall averages were equal to or greater than 4.60. The dimensions that showed the greatest agreement and importance among students were, respectively, problem solving and realism.CONCLUSIONS: In the students' perception, the simulated scenarios were clear and objective in relation to the proposal and the execution. In addition, they felt supported during the learning process, which allowed to explore and solve the problems presented during the simulation. The feedback provided was relevant and provided opportunities for students to reflect on their practices and attitudes. Finally, realism was highlighted as an important aspect by those surveyed.