Intake of wine, beer and spirits and risk of gastric cancer

Abstract

The objective was to study prospectively the relation between quantity and type of alcohol and risk of gastric cancer. In a pooled database from three population studies conducted in 1964-1992, a total of 15,236 men and 13,227 women were followed for a total of 389,051 person-years. During follow-up 122 incident cases of gastric cancer were identified. Total alcohol intake itself was not associated with gastric cancer, but type of alcohol seemed to influence risk. Compared with non-wine drinkers, participants who drank 1-6 glasses of wine had a relative risk ratio of 0.76 (95% confidence interval (CI) 0.50-1.16), whereas those who drank >13 glasses of wine per week had a relative risk ratio of 0.16 (95% CI 0.02-1.18). Linear trend test showed a significant association with a relative risk ratio of 0.60 (95% CI 0.39-0.93) per glass of wine drunk per day. These relations persisted after adjustment for age, gender, educational level, body mass index, smoking habits, inhalation and physical activity. There was no association between beer or spirits drinking and gastric cancer. In conclusion, the present study suggests that a daily intake of wine may prevent development of gastric cancer.

Wine consumption, cognitive function and dementias – A relationship?

“…From prospective population-based studies, there is a clear J-shaped relationship between the consumption of alcoholic beverages such as wine, and the risk of cardiovascular diseases including myocardial infarction, which has been extended to a reduced risk of certain cancers, type 2 diabetes and ischaemic stroke [24][25][26][27][28][29][30][31][32][33][34]. Over the last decade, evidence has accumulated which suggests that this J-shaped relationship could also be extended to the risk of cognitive dysfunction and dementias such as Alzheimer's disease and vascular dementia [35][36][37][38][39][40][41].…”

Alcohol—a universal preventive agent? A critical analysis

“…In addition, Danish researchers have found that moderate wine consumption is associated with lower frequency of cancer in the upper digestive tract [42]; gastric cancer [43]; hip fracture [44]; and lung cancer [45].…”

Alcoholic beverage consumption and gastric cancer risk: A prospective population‐based study in women

“…1 Case-control 2-12 and cohort studies 13-15 on alcohol and gastric cancer published since that review have found either no significant association 3,[5][6][7][11][12][13][14][15] or a statistically significant increased risk of overall [8][9][10] or noncardia gastric cancer 2,4 associated with high alcohol consumption. Despite a large number of epidemiological studies concerning the relation between alcohol consumption and risk of gastric cancer, most have been case-control investigations, which are more susceptible to systematic bias than prospective cohort studies.…”