Intake of Dairy Products, Calcium, and Vitamin D and Risk of Breast Cancer

Myung-Hee, Shin; Holmes, Michelle D.; Hankinson, Susan E.; Wu, Kana; Colditz, Graham A.; Willett, Walter C.

doi:10.1093/jnci/94.17.1301

Cited by 359 publications

(326 citation statements)

References 42 publications

Supporting

Mentioning

285

Contrasting

Unclassified

Order By: Relevance

“…The latter is consistent with other studies, indicating that consuming dairy products twice a day is strongly correlated with protection against breast cancer (OR = 0.04; 95%CI: 0.01-0.15) 24,33,34 . A Uruguayan study highlighted a protective effect from low-fat fermented dairy products 35 .…”

Section: Discussionsupporting

confidence: 92%

Diet and cancer in Northeast Brazil: evaluation of eating habits and food group consumption in relation to breast cancer

et al. 2008

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 92%

Diet and cancer in Northeast Brazil: evaluation of eating habits and food group consumption in relation to breast cancer

et al. 2008

View full text Add to dashboard Cite

“…In a rodent model, calcium reduces fat-induced cell proliferation by maintaining intracellular calcium concentrations (Jacobson et al, 1989) and greater fat intakes has been related to endometrial cancer risk (Bandera et al, 2007b). Calcium has been inversely associated with risk of breast cancer, another hormone-dependent cancer (Mccullough et al, 2005;Shin et al, 2002). Calcium may also influence risk through its metabolic relationship with vitamin D: calcium supplementation lowers 1,25(OH) 2 D levels (Sanchez et al, 1997), theoretically sparing 25(OH)D from conversion to 1,25(OH) 2 D. Substrate preservation may render 25(OH) D more available for endometrial tissue-specific synthesis of 1,25(OH) 2 D.…”

Section: Discussionmentioning

confidence: 99%

Vitamin D and calcium intake in relation to risk of endometrial cancer: A systematic review of the literature

McCullough¹,

Bandera²,

Moore³

et al. 2008

Preventive Medicine

View full text Add to dashboard Cite

Objective-In response to a recent ecologic study of UV exposure and endometrial cancer incidence, we present the epidemiologic evidence on the relation between intake of vitamin D and its metabolically related nutrient, calcium, and the occurrence of endometrial cancer.Methods-We conducted a systematic literature review and meta-analysis of vitamin D and calcium in relation to endometrial cancer, including peer-reviewed manuscripts published up to May 2007. Random and fixed effects summary estimates were computed.Results-Pooled analyses of the three case-control studies of dietary vitamin D and endometrial cancer uncovered heterogeneous results that were not significant in random or fixed effects analyses. Cut-points for the highest vitamin D intakes ranged from >244 to >476 IU/day. Qualitatively similar findings were observed for dietary calcium. Only two studies provided estimates for calcium supplements (random effects OR=0.62, 95% CI 0.39-0.99; fixed effects OR=0.62, 95% CI 0.42-0.93, for top vs bottom category, p for heterogeneity=0.25).Conclusions-The limited epidemiological evidence suggests no relation between endometrial cancer in the ranges of dietary vitamin D examined, and suggests a possible inverse association for calcium from supplements. Prospective studies, ideally including plasma 25(OH) D to estimate vitamin D input from diet and sun exposure, are needed to further explore these hypotheses.

show abstract

“…The greatest difference among consumers of specific food groups was seen in the avoidance of milk products in Australian patients. This is an interesting finding, since the scientific data on the risk of breast cancer and milk products is controversial (Shin et al, 2002;Voorrips et al, 2002). In Finland, milk is still an important component of the diet and a large variety of low-lactose and lactose-free milks are available.…”

Section: Dietary Attitudes and Changes E Salminen Et Almentioning

confidence: 98%

Dietary attitudes and changes as well as use of supplements and complementary therapies by Australian and Finnish women following the diagnosis of breast cancer

et al. 2003

View full text Add to dashboard Cite

Objective: This study investigated self-reported dietary attitudes and changes, and use of complementary approaches among breast cancer patients in relation to age, education and time since diagnosis. Design and setting: Australian (ABC, N ¼ 215) and Finnish (FBC, N ¼ 139) breast cancer patients were surveyed at the university cancer centres with voluntary participation. Logistic regression models were used to adjust for differences in demographic patient characteristics between the groups. The influence of demographic variables was further studied separately or combined. Results: In all, 30% of FBC patients and 39% of ABC patients reported having changed their diet (P ¼ 0.033). Higher education, younger age and longer time from diagnosis were significantly associated with the probability of changes. The main changes reported included reduced consumption of animal fat, sugar and red meat, and increased consumption of fruits and vegetables. In all, 6% of ABC and 4% of FBC patients had stopped smoking and 24% of ABC and 27% of FBC patients reported to have increased their level of physical exercise. Choices were associated with age (Po0.007), length of the disease history (P o0.01) and level of education (P o0.002). Conclusion: One-third of breast cancer patients surveyed reported to have changed their dietary habits. Both populations reported a need for dietary and lifestyle counselling. This need was experienced as poorly recognised by the physicians at present, and warrants future studies in dietary behaviour of breast cancer patients.

show abstract

Intake of Dairy Products, Calcium, and Vitamin D and Risk of Breast Cancer

Cited by 359 publications

References 42 publications

Diet and cancer in Northeast Brazil: evaluation of eating habits and food group consumption in relation to breast cancer

Diet and cancer in Northeast Brazil: evaluation of eating habits and food group consumption in relation to breast cancer

Vitamin D and calcium intake in relation to risk of endometrial cancer: A systematic review of the literature

Dietary attitudes and changes as well as use of supplements and complementary therapies by Australian and Finnish women following the diagnosis of breast cancer

Contact Info

Product

Resources

About