1957
DOI: 10.1016/s0140-6736(57)91070-x
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Insulin Treatment of Schizophrenia

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Cited by 77 publications
(23 citation statements)
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“…After the discovery of an effective antipsychotic neuroleptic, investigators became confident and bold enough to risk conducting adequately controlled studies of insulin coma. By excluding all confounders, they demonstrated that the crucial ingredients were the vastly better nursing care the insulin coma patients received, the better morale of their doctors and the social cohesion of the patient treatment groups (Cramand, 1987) rather than any effect of the insulin-induced coma per se (Ackner et al , 1957). The world literature reviewed by Koenig et al (2001) asserts that greater religious involvement reduces depressive symptomatology.…”
Section: Connection With Psychiatrymentioning
confidence: 99%
“…After the discovery of an effective antipsychotic neuroleptic, investigators became confident and bold enough to risk conducting adequately controlled studies of insulin coma. By excluding all confounders, they demonstrated that the crucial ingredients were the vastly better nursing care the insulin coma patients received, the better morale of their doctors and the social cohesion of the patient treatment groups (Cramand, 1987) rather than any effect of the insulin-induced coma per se (Ackner et al , 1957). The world literature reviewed by Koenig et al (2001) asserts that greater religious involvement reduces depressive symptomatology.…”
Section: Connection With Psychiatrymentioning
confidence: 99%
“…Nine years later, a randomized controlled trial of ICT reported that there was no statistically significant difference in outcome when patients who had undergone ICT were compared with those who had been put into a barbiturate coma (Ackner et al . ). To opponents of ICT, this RCT provided definitive support for their case.…”
Section: Resultsmentioning
confidence: 97%
“…Of these nine, six had finished a course of insulin coma, one a course of barbiturate treatment, and one a course of cardiazol treatment a week or two before being tested for the first time. There is no evidence that the type of physical treatment given affected the outcome (Ackner, Harris, and Oldham, 1957).…”
Section: Nufferno Test and Affectmentioning
confidence: 99%
“…With regard to their clinical state they were divided into three groups, namely, recovered, residual defect, and still psychotic, as defined in a previous paper (Ackner, Harris, and Oldham, 1957). There is a trend towards the association of higher speeds on the unstressed version of the test with a more favourable outcome and of high stressgain scores with unfavourable outcome but the difference between the scores of the patients who later recovered and the scores of those who did not does not attain a satisfactory degree of statistical significance and is too small to render it useful in prediction.…”
Section: Nufferno Test and Affectmentioning
confidence: 99%