Insulin resistance by the triglyceride-glucose index in a rural Brazilian population

Ferreira, Júlia Rabelo Santos; Zandonade, Eliana; Bezerra, Olívia Maria de Paula Alves; Salaroli, Luciane Bresciani

doi:10.20945/2359-3997000000509

Cited by 6 publications

(8 citation statements)

References 33 publications

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“…It is also worth noting that being overweight increased the farmer's chance of having two or more cardiovascular risk factors by more than twice. In this same population, a prevalence of 33.8% of insulin resistance was found, with overweight or obesity increasing by about three times the risk of an individual presenting this condition [5].…”

Section: Introductionmentioning

confidence: 75%

“…The performance of the conicity index as an indicator of abdominal obesity from the MetS components has been demonstrated in numerous studies, but there is still no consensus on the cut points, which vary according to the population, sex and age [9,[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. Until then, no cut point was determined for this index in the Brazilian rural population, which justifies the importance of the present study.…”

Section: Introductionmentioning

confidence: 93%

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Cut Points of the Conicity Index and Associated Factors in Brazilian Rural Workers

Prado¹,

Martins²,

Cremonini³

et al. 2022

Preprint

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(1) Background: Metabolic syndrome is associated with cardiovascular complications. Therefore, this study aims to establish cut points for the conicity index based on the components of the metabolic syndrome and to associate it with characteristics sociodemographic, food consumption and occupational factors in Brazilian rural workers; (2) Methods: Cross-sectional study carried out with farmers. The receiver operating characteristic curve was calculated and the cutoff points for the conicity index were identified by the area under the curve, sensitivity and specificity. The variables included in the binary logistic regression analysis were selected by considering p &lt; 0.20 in the bivariate test; (3) Results: The cut points were similar in females according to both criteria, resulting in a single cut-off of 1.269. In males, the cut points showed differences, resulting in 1.272 according to the NCEP-ATP III and 1.252 according to the IDF. We have shown that younger people, those who work more than 40 hours a week and the lowest contribution of culinary ingredients are associated with increased odds of abdominal obesity. While the consumption of the products they sell or produce decreases these chances; (4) Conclusions: The conicity index showed high discriminatory power for the identification of abdominal obesity in rural workers.

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Section: Introductionmentioning

confidence: 75%

Section: Introductionmentioning

confidence: 93%

Cut Points of the Conicity Index and Associated Factors in Brazilian Rural Workers

Prado¹,

Martins²,

Cremonini³

et al. 2022

Preprint

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“…TyG index is a simple surrogate for IR, which has been implicated as a factor in cardiovascular disease [20][21][22][23]. Accumulating retrospective studies have indicated that high TyG index levels seemed to be associated with an increased risk of major adverse cardiovascular events (MACEs) [24][25][26][27].…”

Section: Discussionmentioning

confidence: 99%

Association between Triglyceride glucose index and severity of diabetic foot ulcers in type2 diabetes mellitus

Zhang

Chen

Wang

et al. 2023

Preprint

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Background: Triglyceride glucose (TyG) index is a good surrogate biomarker to evaluate insulin resistance (IR). The study aimed to investigate whether the TyG index is related to the severity of diabetic foot ulcers (DFUs) in patients with type2 diabetes mellitus (T2DM). Methods: A total of 1059 T2DM patients were enrolled in this observational, retrospective, single-center study. TyG index was calculated as ln[fasting triglycerides (mg/dl)×fasting glucose (mg/ dl)/2]. The severity of DFUs was classified into mild-to-moderate DFUs (Wagner grade score <3) and severe DFUs (Wagner grade score ≥3) based on Wagner classification. Patients were stratified according to the tertiles of TyG index. Logistic regression models were implemented to explore the association between TyG index and the severity of DFUs. Subgroup analyses were used to verify the reliability of results. Results: Compared with the reference lowest TyG tertile (T1), the highest tertile (T3) was associated with 0.377-fold increased risk of prevalence of severe DFUs (odds ratio [OR] 1.377, 95% confidence interval [CI] 1.017-1.865) (P =0.039). After adjusting for potential confounders, the multivariable-adjusted OR and 95% CI were 1.506 (1.079-2.103) (P =0.016) in patients with highest tertile. Moreover, subgroup analyses indicated that the association was stronger among men, patients with age ≥ 65 years, duration of diabetes more than 10 years, or without PAD. Conclusions: Elevated TyG index is independently associated with severity of DFUs even after adjusting conventional confounders.

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“…It is also worth noting that being overweight more than doubled the farmers’ chances of having two or more cardiovascular risk factors. In this same population, a 33.8% prevalence of insulin resistance was found, with obesity or being overweight increasing the risk of an individual presenting this condition by about three times [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

“…The performance of the conicity index as an indicator of abdominal obesity from the MetS components has been demonstrated in numerous studies, but there is still no consensus on the cut points, which vary according to population, sex and age [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ]. Until then, no cut point has been determined for this index in the Brazilian rural population, which justifies the importance of the present study.…”

Section: Introductionmentioning

confidence: 99%

Cut Points of the Conicity Index and Associated Factors in Brazilian Rural Workers

Prado

Martins²,

Cremonini³

et al. 2022

Nutrients

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(1) Background: Metabolic syndrome is associated with cardiovascular complications. Therefore, this study aims to establish cut points for the conicity index based on the components of metabolic syndrome and to associate it with characteristic sociodemographic, food consumption and occupational factors in Brazilian rural workers; (2) Methods: A cross-sectional study carried out with farmers. The receiver operating characteristic curve was calculated and the cut-off points for the conicity index were identified by the area under the curve, sensitivity and specificity. The variables included in the binary logistic regression analysis were selected by considering p < 0.20 in the bivariate test; (3) Results: The cut points were similar in females according to both criteria, resulting in a single cut-off of 1.269. In males, the cut points showed differences, resulting in 1.272 according to the NCEP-ATP III and 1.252 according to the IDF. We have shown that younger people, those who work more than 40 h a week and the lowest contribution of culinary ingredients are associated with increased odds of abdominal obesity, while the consumption of the products they sell or produce decreases these chances; (4) Conclusions: The conicity index showed high discriminatory power for the identification of abdominal obesity in rural workers. Therefore, there is a need to improve eating habits and promote healthier eating environments for individuals, respecting traditional food culture, mainly to contain the advance of MS in rural areas.

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Insulin resistance by the triglyceride-glucose index in a rural Brazilian population

Cited by 6 publications

References 33 publications

Cut Points of the Conicity Index and Associated Factors in Brazilian Rural Workers

Cut Points of the Conicity Index and Associated Factors in Brazilian Rural Workers

Association between Triglyceride glucose index and severity of diabetic foot ulcers in type2 diabetes mellitus

Cut Points of the Conicity Index and Associated Factors in Brazilian Rural Workers

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